[HTML][HTML] Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
…, NG Martin, GW Montgomery, AD Murray… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …
with many important life outcomes. We combine cognitive and genetic data from the …
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic
architecture or its genetic relationship with other disorders. To discover loci associated …
architecture or its genetic relationship with other disorders. To discover loci associated …
Neural mechanisms of imitation and 'mirror neuron'functioning in autistic spectrum disorder
…, GD Waiter, A Gilchrist, DI Perrett, AD Murray… - Neuropsychologia, 2006 - Elsevier
An association between autistic spectrum disorder and imitative impairment might result from
dysfunction in mirror neurons (MNs) that serve to relate observed actions to motor codings. …
dysfunction in mirror neurons (MNs) that serve to relate observed actions to motor codings. …
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
…, NG Martin, C Matalliotaki, M Matalliotakis, AD Murray… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
[HTML][HTML] Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N= 112 117)
…, LS Hall, S Padmanabhan, AD Murray… - Molecular …, 2017 - nature.com
Alcohol consumption has been linked to over 200 diseases and is responsible for over 5%
of the global disease burden. Well-known genetic variants in alcohol metabolizing genes, for …
of the global disease burden. Well-known genetic variants in alcohol metabolizing genes, for …
An overview of prevalence, determinants and health outcomes of polypharmacy
M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm of …
multimorbidity in the ageing population worldwide. Our understanding of the potential harm of …
What provides cerebral reserve?
RT Staff, AD Murray, IJ Deary, LJ Whalley - Brain, 2004 - academic.oup.com
The cerebral reserve hypothesis is a heuristic concept used to explain apparent protection
from the onset of cerebral disease and/or cognitive decline in old age. A significant obstacle …
from the onset of cerebral disease and/or cognitive decline in old age. A significant obstacle …
[HTML][HTML] Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease
…, DJ Wischik, P Bentham, AD Murray… - Journal of …, 2015 - content.iospress.com
Background: As tau aggregation pathology correlates with clinical dementia in Alzheimer’s
disease (AD), a tau aggregation inhibitor (TAI) could have therapeutic utility. …
disease (AD), a tau aggregation inhibitor (TAI) could have therapeutic utility. …
A voxel-based investigation of brain structure in male adolescents with autistic spectrum disorder
GD Waiter, JHG Williams, AD Murray, A Gilchrist… - Neuroimage, 2004 - Elsevier
Autistic spectrum disorder (ASD) has been associated with abnormal neuroanatomy in
many imaging and neuropathological studies. Both global brain volume differences and …
many imaging and neuropathological studies. Both global brain volume differences and …
Brain White Matter Hyperintensities: Relative Importance of Vascular Risk Factors in Nondemented Elderly People1
AD Murray, RT Staff, SD Shenkin, IJ Deary, JM Starr… - Radiology, 2005 - pubs.rsna.org
PURPOSE: To prospectively determine whether there is an association between brain white
matter signal hyperintensities on magnetic resonance (MR) images and potential risk …
matter signal hyperintensities on magnetic resonance (MR) images and potential risk …