User profiles for Alison E. Wright

Alison E Wright

University of Sheffield
Verified email at sheffield.ac.uk
Cited by 2376

Sex chromosome evolution: so many exceptions to the rules

…, DCH Metzger, I Darolti, AE Wright… - Genome biology and …, 2020 - academic.oup.com
Genomic analysis of many nonmodel species has uncovered an incredible diversity of sex
chromosome systems, making it possible to empirically test the rich body of evolutionary …

[HTML][HTML] How to make a sex chromosome

AE Wright, R Dean, F Zimmer, JE Mank - Nature communications, 2016 - nature.com
Sex chromosomes can evolve once recombination is halted between a homologous pair of
chromosomes. Owing to detailed studies using key model systems, we have a nuanced …

Sexual selection drives evolution and rapid turnover of male gene expression

PW Harrison, AE Wright, F Zimmer… - Proceedings of the …, 2015 - National Acad Sciences
The profound and pervasive differences in gene expression observed between males and
females, and the unique evolutionary properties of these genes in many species, have led to …

How to identify sex chromosomes and their turnover

DH Palmer, TF Rogers, R Dean, AE Wright - Molecular ecology, 2019 - Wiley Online Library
Although sex is a fundamental component of eukaryotic reproduction, the genetic systems
that control sex determination are highly variable. In many organisms the presence of sex …

[HTML][HTML] Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation

AE Wright, I Darolti, NI Bloch, V Oostra… - Nature …, 2017 - nature.com
Sex chromosomes evolve once recombination is halted between a homologous pair of
chromosomes. The dominant model of sex chromosome evolution posits that recombination is …

Detecting signatures of selection on gene expression

…, TF Rogers, JE Mank, CR Cooney, AE Wright - Nature Ecology & …, 2022 - nature.com
A substantial amount of phenotypic diversity results from changes in gene expression levels
and patterns. Understanding how the transcriptome evolves is therefore a key priority in …

[HTML][HTML] Masculinization of gene expression is associated with exaggeration of male sexual dimorphism

MA Pointer, PW Harrison, AE Wright, JE Mank - PLoS genetics, 2013 - journals.plos.org
Gene expression differences between the sexes account for the majority of sexually dimorphic
phenotypes, and the study of sex-biased gene expression is important for understanding …

The evolution of gene expression and the transcriptome–phenotype relationship

PW Harrison, AE Wright, JE Mank - Seminars in cell & developmental …, 2012 - Elsevier
Changes in gene expression underlie the adaptive evolution in many complex phenotypes,
and the recent increase in the availability of multi-species comparative transcriptome data …

ngsLD: evaluating linkage disequilibrium using genotype likelihoods

EA Fox, AE Wright, M Fumagalli, FG Vieira - Bioinformatics, 2019 - academic.oup.com
Motivation Linkage disequilibrium (LD) measures the correlation between genetic loci and
is highly informative for association mapping and population genetics. As many studies rely …

W chromosome expression responds to female-specific selection

HK Moghadam, MA Pointer, AE Wright… - Proceedings of the …, 2012 - National Acad Sciences
The W chromosome is predicted to be subject to strong female-specific selection stemming
from its female-limited inheritance and therefore should play an important role in female …