Sarcopenia, the degenerative loss of skeletal muscle mass, quality and strength, lacks early
diagnostic tools and new therapeutic strategies to prevent the frailty-to-disability transition …

Insulin resistance is a key event in type 2 diabetes onset and a major comorbidity of obesity.
It results from a combination of fat excess–triggered defects, including lipotoxicity and …

To fight against metabolic disorders such as insulin resistance, new alimentary behaviors are
developed. For instance, hyperproteined, gluten-free, or collagen-enriched diets could be …

Despite decades of effort in understanding pancreatic ductal adenocarcinoma (PDAC), there
is still a lack of innovative targeted therapies for this devastating disease. Herein, we report …

Numerous recent studies have shown that in the continuum of cardiovascular diseases, the
measurement of arterial stiffness has powerful predictive value in cardiovascular risk and …

Megakaryocytes (MKs) come from a complex process of hematopoietic progenitor maturation
within the bone marrow that gives rise to de novo circulating platelets. Bone marrow …

Dysregulations of lipid metabolism in the liver may trigger steatosis progression, leading to
potentially severe clinical consequences such as nonalcoholic fatty liver diseases (NAFLDs). …

Kidney function is altered by age together with a declined filtration capacity of 5–10% per
decade after 35 years. Renal aging shares many characteristics with chronic kidney disease. …

Vascular stiffness is often the main cause of arterial hypertension and its complications
including atherosclerosis, observed during obesity. However, the mechanisms leading to this …

… Grâce à toi et Alizée Dortignac je suis allée deux fois en boîte en moins d’un mois, le record
de ma vie. Alizée tu étais un petit bébé à ton arrivée, tu es et resteras toujours le bébé de l’…