[HTML][HTML] The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer's disease

BDC Boon, M Bulk, AJ Jonker, THJ Morrema… - Acta …, 2020 - Springer
Alzheimer’s disease (AD) is characterized by amyloid-beta (Aβ) deposits, which come in
myriad morphologies with varying clinical relevance. Previously, we observed an atypical Aβ …

[HTML][HTML] Prefrontal cortical ChAT-VIP interneurons provide local excitation by cholinergic synaptic transmission and control attention

…, AA Galakhova, AJ Khalil, T Kroon, AJ Jonker… - Nature …, 2019 - nature.com
Neocortical choline acetyltransferase (ChAT)-expressing interneurons are a subclass of
vasoactive intestinal peptide (ChAT-VIP) neurons of which circuit and behavioural function are …

[HTML][HTML] Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease

…, AJ Jonker, T Gasser, B Winner, J Winkler… - Nature …, 2022 - nature.com
Parkinson’s disease (PD) as a progressive neurodegenerative disorder arises from multiple
genetic and environmental factors. However, underlying pathological mechanisms remain …

[PDF][PDF] NMDA receptors control cue-outcome selectivity and plasticity of orbitofrontal firing patterns during associative stimulus-reward learning

…, M Vinck, V Tijms, IRS Ferreira, AJ Jonker… - Neuron, 2012 - cell.com
Neural activity in orbitofrontal cortex has been linked to flexible representations of stimulus-outcome
associations. Such value representations are known to emerge with learning, but …

[HTML][HTML] Axonal degeneration in the anterior insular cortex is associated with Alzheimer's co-pathology in Parkinson's disease and dementia with Lewy bodies

…, LE Jonkman, JJ Bol, E Timmermans, AJ Jonker… - Translational …, 2022 - Springer
Background Axons, crucial for impulse transmission and cellular trafficking, are thought to be
primary targets of neurodegeneration in Parkinson’s disease (PD) and dementia with Lewy …

Efferent connections of the striatum and the nucleus accumbens in the lizard Gekko gecko

FT Russchen, AJ Jonker - Journal of Comparative Neurology, 1988 - Wiley Online Library
The efferent connections of the striatum and the nucleus accumbens of the lizard Gekko
gecko were studied with the anterograde tracer Phaseolus vulgaris‐ leucoagglutinin (PHA‐L). …

[HTML][HTML] Distinct tau and alpha-synuclein molecular signatures in Alzheimer's disease with and without Lewy bodies and Parkinson's disease with dementia

…, NAC Deshayes, JJP Breve, JGJM Bol, AJ Jonker… - Acta …, 2024 - Springer
Alpha-synuclein (aSyn) pathology is present in approximately 50% of Alzheimer’s disease (AD)
cases at autopsy and might impact the age-of-onset and disease progression in AD. …

Comparative Analysis of Vasotocin-Like Immunoreactivity in the Brain of the Turtle Pseudemys scripta elegans and the Snake Python regius (Part 2 of 2)

WJAJ Smeets, JJ Sevensma, AJ Jonker - Brain, Behavior and Evolution, 1990 - karger.com
The distribution of vasotocin in the brains of the turtle Pseudemys scripta elegans and the
snake Python regius was studied with immunohistochemical methods. In both species, …

Distribution of Dopamine in the Forebrain and Midbrain of the Red-Eared Turtle, Pseudemys scripta elegans, Reinvestigated Using Antibodies against Dopamine …

WJAJ Smeets, AJ Jonker, PV Hoogland - Brain, Behavior and Evolution, 1987 - karger.com
The distribution of dopamine (DA) immunoreactivy in the forebrain and midbrain of the red-eared
turtle, Pseudemys scripta elegans, was studied using recently developed antibodies …

Compartment‐specific changes in striatal neuronal activity during expression of amphetamine sensitization are the result of drug hypersensitivity

…, SDC Van Leeuwen, L Hof, AJ Jonker… - European Journal of …, 2002 - Wiley Online Library
Repeated exposure to drugs of abuse induces behavioural sensitization, ie a persistent
hypersensitivity to the psychomotor stimulant effects of these drugs. This may be the result of …