Deciphering the Fluorine Code The Many Hats Fluorine Wears in a Protein Environment

AA Berger, JS Völler, N Budisa… - Accounts of chemical …, 2017 - ACS Publications
Conspectus Deciphering the fluorine code is how we describe not only the focus of this
Account, but also the systematic approach to studying the impact of fluorine’s incorporation on …

Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles

…, CJ Schipp, V Kubyshkin, AA Berger… - ACS Central …, 2020 - ACS Publications
Organofluorine compounds are known to be toxic to a broad variety of living beings in
different habitats, and chemical fluorination has been historically exploited by mankind for the …

[HTML][HTML] Fluorine teams up with water to restore inhibitor activity to mutant BPTI

S Ye, B Loll, AA Berger, U Mülow, C Alings… - Chemical …, 2015 - pubs.rsc.org
Introducing fluorine into molecules has a wide range of effects on their physicochemical
properties, often desirable but in most cases unpredictable. The fluorine atom imparts the C–F …

[HTML][HTML] Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis

S Ye, AA Berger, D Petzold, O Reimann… - Beilstein journal of …, 2010 - beilstein-journals.org
This article describes the chemical aminoacylation of the yeast phenylalanine suppressor
tRNA with a series of amino acids bearing fluorinated side chains via the hybrid dinucleotide …

[HTML][HTML] Escherichia coli adapts metabolically to 6-and 7-fluoroindole, enabling proteome-wide fluorotryptophan substitution

C Treiber-Kleinke, AA Berger, L Adrian… - Frontiers in Synthetic …, 2024 - frontiersin.org
Nature has scarcely evolved a biochemistry around fluorine. However, modern science has
shown that fluorinated organic molecules are suitable building blocks for biopolymers, from …

[HTML][HTML] Investigations from the Belly of the Beast: N-Terminally Labeled Incretin Peptides That Are Both Potent Receptor Agonists and Stable to Protease Digestion

AA Berger, J Leppkes, B Koksch - 2021 - ACS Publications
An N-alkylation strategy to impart protease resistance to therapeutic peptides for type 2
diabetes management also proves nonperturbative to agonist potency.

Laboratory evolution of Escherichia coli enables life based on fluorinated amino acids

…, L Sinn, D Petras, CJ Schipp, V Kubyshkin, AA Berger… - bioRxiv, 2019 - biorxiv.org
Organofluorine compounds are toxic to various living beings in different habitats. On the
other hand, fluorine incorporation into single proteins via related amino acid analogues has …

[CITATION][C] Fluorinated Protease Substrates Show Position-Dependent Degradation

S Huhmann, AA Berger, B Koksch - Frontiers of Organofluorine …, 2020 - World Scientific
… Susanne Huhmann, Allison Ann Berger, and Beate Koksch* … 520 Susanne Huhmann, Allison
Ann Berger & Beate Koksch … 522 Susanne Huhmann, Allison Ann Berger & Beate Koksch …

Catalytically active peptide–gold nanoparticle conjugates: prospecting for artificial enzymes

DJ Mikolajczak, AA Berger… - Angewandte Chemie …, 2020 - Wiley Online Library
The self‐assembly of peptides onto the surface of gold nanoparticles has emerged as a
promising strategy towards the creation of artificial enzymes. The resulting high local peptide …

[PDF][PDF] Sleep/Wake Disturbances in People With Cancer and Their Caregivers: State of the Science.

AM Berger, KP Parker… - Oncology nursing …, 2005 - researchgate.net
Purpose/Objectives: To review the state of the science on sleep/wake disturbances in
people with cancer and their caregivers. Data Sources: Published articles, books and book …