Extended-spectrum beta-lactamases: a brief clinical update
AMW Malloy, JM Campos - The Pediatric infectious disease …, 2011 - journals.lww.com
Beta-lactamase enzymes (BLs) have be-come the most worrisome mediators of antimicrobial
resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have …
resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have …
[HTML][HTML] SARS-CoV-2 ferritin nanoparticle vaccine induces robust innate immune activity driving polyfunctional spike-specific T cell responses
…, JR Currier, E Bergmann-Leitner, AMW Malloy… - npj Vaccines, 2021 - nature.com
The emergence of variants of concern, some with reduced susceptibility to COVID-19
vaccines underscores consideration for the understanding of vaccine design that optimizes …
vaccines underscores consideration for the understanding of vaccine design that optimizes …
[HTML][HTML] Quantitative and qualitative deficits in neonatal lung-migratory dendritic cells impact the generation of the CD8+ T cell response
TJ Ruckwardt, AMW Malloy, KM Morabito… - PLoS …, 2014 - journals.plos.org
CD103+ and CD11b+ populations of CD11c+MHCIIhi murine dendritic cells (DCs) have been
shown to carry antigens from the lung through the afferent lymphatics to mediastinal lymph …
shown to carry antigens from the lung through the afferent lymphatics to mediastinal lymph …
Adverse effects and antibody titers in response to the BNT162b2 mRNA COVID-19 vaccine in a prospective study of healthcare workers
…, AR Lindrose, AL Snow, AMW Malloy… - Open Forum …, 2022 - academic.oup.com
Background The relationship between postvaccination symptoms and strength of antibody
responses is unclear. The goal of this study was to determine whether adverse effects caused …
responses is unclear. The goal of this study was to determine whether adverse effects caused …
Durability of SARS-CoV-2–specific T-cell responses at 12 months postinfection
…, AL Snow, TH Burgess, AMW Malloy - The Journal of …, 2021 - academic.oup.com
Background Characterizing the longevity and quality of cellular immune responses to severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enhances understanding of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enhances understanding of …
[HTML][HTML] Durability of antibody response and frequency of SARS-CoV-2 infection 6 months after COVID-19 vaccination in healthcare workers
…, CA Duplessis, DR Tribble, AMW Malloy… - Emerging infectious …, 2022 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist
6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-…
6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-…
[HTML][HTML] Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice
TJ Ruckwardt, AMW Malloy, E Gostick, DA Price… - PLoS …, 2011 - journals.plos.org
Following respiratory syncytial virus infection of adult CB6F1 hybrid mice, a predictable CD8+
T cell epitope hierarchy is established with a strongly dominant response to a K d -…
T cell epitope hierarchy is established with a strongly dominant response to a K d -…
[HTML][HTML] SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies
This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh)
and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-…
and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-…
[HTML][HTML] Increased innate immune activation induces protective RSV-specific lung-resident memory T cells in neonatal mice
AMW Malloy, Z Lu, M Kehl, JP DaMata… - Mucosal …, 2023 - Elsevier
Young infants frequently experience respiratory tract infections, yet vaccines designed to
provide mucosal protection are lacking. Localizing pathogen-specific cellular and humoral …
provide mucosal protection are lacking. Localizing pathogen-specific cellular and humoral …
Consequences of immature and senescent immune responses for infection with respiratory syncytial virus
AMW Malloy, AR Falsey, TJ Ruckwardt - Challenges and opportunities for …, 2013 - Springer
Infants in the first 6 months of life and older adults (>65 years of age) are disproportionately
burdened with respiratory syncytial virus (RSV)-associated morbidity and mortality. While …
burdened with respiratory syncytial virus (RSV)-associated morbidity and mortality. While …