Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea
Regeneration requires the coordination of stem cells, their progeny and distant differentiated
tissues. Here, we present a comprehensive atlas of whole-body regeneration in Schmidtea …
tissues. Here, we present a comprehensive atlas of whole-body regeneration in Schmidtea …
[HTML][HTML] Off-target piRNA gene silencing in Drosophila melanogaster rescued by a transposable element insertion
…, C Cummings, M Barragan, RR Egidy, AR Scott… - PLoS …, 2023 - journals.plos.org
Transposable elements (TE) are selfish genetic elements that can cause harmful mutations.
In Drosophila, it has been estimated that half of all spontaneous visible marker phenotypes …
In Drosophila, it has been estimated that half of all spontaneous visible marker phenotypes …
Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation
JA Morrison, R McLennan, JM Teddy, AR Scott… - …, 2021 - journals.biologists.com
The dynamics of multipotent neural crest cell differentiation and invasion as cells travel
throughout the vertebrate embryo remain unclear. Here, we preserve spatial information to derive …
throughout the vertebrate embryo remain unclear. Here, we preserve spatial information to derive …
[HTML][HTML] Multisite evaluation of next-generation methods for small RNA quantification
…, J Koeman, A Perera, AR Scott… - Journal of …, 2020 - ncbi.nlm.nih.gov
Small RNAs (smRNAs) are important regulators of many biologic processes and are now
most frequently characterized using Illumina sequencing. However, although standard RNA …
most frequently characterized using Illumina sequencing. However, although standard RNA …
Molecular Control of Circuit Plasticity and the Permanence of Imprinted Odor Memory
Behavioral imprinting is a distinct form of learning that has a lifelong impact on social
interactions and affectional behaviors 1 - 4 . Unlike other forms of memory, imprinting does not …
interactions and affectional behaviors 1 - 4 . Unlike other forms of memory, imprinting does not …
Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution
…, T Chiremba, S Malloy, AR Scott, AG Perera, R Yu - bioRxiv, 2024 - biorxiv.org
We have generated single cell transcriptomic atlases of vomeronasal organs (VNO) from
juvenile and adult mice. Combined with spatial molecular imaging, we uncover a distinct, …
juvenile and adult mice. Combined with spatial molecular imaging, we uncover a distinct, …
Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration.
A Ortega Granillo, D Zamora, RR Schnittker, AR Scott… - bioRxiv, 2024 - biorxiv.org
Injury is a common occurrence in the life of organisms. Because the extent of damage cannot
be predicted, injured organisms must determine how much tissue needs to be restored. It is …
be predicted, injured organisms must determine how much tissue needs to be restored. It is …
Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion
JA Morrison, R McLennan, JM Teddy, AR Scott… - BioRxiv, 2020 - biorxiv.org
The vertebrate branchial arches that give rise to structures of the head, neck, and heart form
with very dynamic tissue growth and well-choreographed neural crest, ectoderm, and …
with very dynamic tissue growth and well-choreographed neural crest, ectoderm, and …
Identification of rare transient somatic cell states induced by injury and required for whole-body regeneration
…, CE Brewster, AM Kent, FG Mann Jr, S Chen, AR Scott… - bioRxiv, 2020 - biorxiv.org
Regeneration requires functional coordination of stem cells, their progeny, and differentiated
cells. Past studies have focused on regulation of stem cell identity and proliferation near to …
cells. Past studies have focused on regulation of stem cell identity and proliferation near to …
Germline gene de-silencing by a transposon insertion is triggered by an altered landscape of local piRNA biogenesis
…, C Cummings, M Barragan, R Egidy, AR Scott… - bioRxiv, 2020 - biorxiv.org
Transposable elements (TE) are selfish genetic elements that can cause harmful mutations.
In Drosophila, it has been estimated that half of all spontaneous visible marker phenotypes …
In Drosophila, it has been estimated that half of all spontaneous visible marker phenotypes …