Glioblastomas are invasive and aggressive tumors of the brain, generally considered to arise
from glial cells. A subset of these cancers develops from lower-grade gliomas and can thus …

In this study, approximately 40 endogenous metabolites were identified and quantified by 1
H NMR in urine samples from male rats dosed with two proximal tubule toxicants, cisplatin …

Despite the remarkable clinical response of melanoma harboring BRAF mutations to BRAF
inhibitors (BRAFi), most tumors become resistant. Here, we identified the downregulation of …

Despite advances in cancer treatment, the 5-year mortality rate for oral cancers (OC) is 40%,
mainly due to the lack of early diagnostics. To advance early diagnostics for high-risk and …

Melanoma is one of the most lethal skin cancers worldwide, primarily because of its propensity
to metastasize. Thus, the elucidation of mechanisms that govern metastatic propensity is …

A functional readout of the gut microbiome is necessary to enable precise control of the gut
microbiome’s functions, which support human health and prevent or minimize a wide range …

Limiting postprandial glycemic response (PPGR) is an important intervention in reducing the
risk of chronic metabolic diseases and has been shown to impart significant health benefits …

To prevent and treat chronic diseases, including cancer, a global application of systems
biology is needed. We report here a whole blood transcriptome test that needs only 50 μl of …

Background: A number of epidemiological studies have identified statistical associations
between persistent organic pollutants (POPs) and metabolic diseases, but testable hypotheses …

Limiting post-meal glycemic response is an important factor in reducing the risk of chronic
metabolic diseases, and contributes to significant health benefits in people with elevated …