Genome Sequencing and Mapping Reveal Loss of Heterozygosity as a Mechanism for Rapid Adaptation in the Vegetable Pathogen Phytophthora capsici

…, D Platt, A Salamov, A Savidor… - Molecular Plant …, 2012 - Am Phytopath Society
The oomycete vegetable pathogen Phytophthora capsici has shown remarkable adaptation
to fungicides and new hosts. Like other members of this destructive genus, P. capsici has an …

[HTML][HTML] Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans

…, Q Ren, S Restrepo, S Roy, A Sadanandom, A Savidor… - Nature, 2009 - nature.com
Phytophthora infestans is the most destructive pathogen of potato and a model organism for
the oomycetes, a distinct lineage of fungus-like eukaryotes that are related to organisms …

[HTML][HTML] Microbiota-modulated metabolites shape the intestinal microenvironment by regulating NLRP6 inflammasome signaling

…, G Zilberman-Schapira, JA Mahdi, E David, A Savidor… - Cell, 2015 - cell.com
Host-microbiome co-evolution drives homeostasis and disease susceptibility, yet regulatory
principles governing the integrated intestinal host-commensal microenvironment remain …

Phytophthora Genome Sequences Uncover Evolutionary Origins and Mechanisms of Pathogenesis

…, JKC Rose, Y Sakihama, AA Salamov, A Savidor… - Science, 2006 - science.org
Draft genome sequences have been determined for the soybean pathogen Phytophthora
sojae and the sudden oak death pathogen Phytophthora ramorum. Oömycetes such as these …

Communication between viruses guides lysis–lysogeny decisions

…, Y Peleg, S Melamed, A Leavitt, A Savidor… - Nature, 2017 - nature.com
Temperate viruses can become dormant in their host cells, a process called lysogeny. In every
infection, such viruses decide between the lytic and the lysogenic cycles, that is, whether …

Dysregulated mi RNA biogenesis downstream of cellular stress and ALS‐causing mutations: a new mechanism for ALS

…, B Alajajian, IZ Ben‐Dov, J Aebischer, A Savidor… - The EMBO …, 2015 - embopress.org
Interest in RNA dysfunction in amyotrophic lateral sclerosis ( ALS ) recently aroused upon
discovering causative mutations in RNA ‐binding protein genes. Here, we show that extensive …

ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration

A Aharonov, A Shakked, KB Umansky, A Savidor… - Nature cell …, 2020 - nature.com
Cardiomyocyte loss after injury results in adverse remodelling and fibrosis, inevitably leading
to heart failure. The ERBB2–Neuregulin and Hippo–YAP signalling pathways are key …

Disturbance of the bacterial cell wall specifically interferes with biofilm formation

…, Y Oppenheimer‐Shaanan, A Savidor… - Environmental …, 2015 - Wiley Online Library
In nature, bacteria communicate via chemical cues and establish complex communities referred
to as biofilms, wherein cells are held together by an extracellular matrix. Much research …

MS1-based label-free proteomics using a quadrupole orbitrap mass spectrometer

T Shalit, D Elinger, A Savidor… - Journal of proteome …, 2015 - ACS Publications
Presented is a data set for benchmarking MS1-based label-free quantitative proteomics using
a quadrupole orbitrap mass spectrometer. Escherichia coli digest was spiked into a HeLa …

BcXYG1, a Secreted Xyloglucanase from Botrytis cinerea, Triggers Both Cell Death and Plant Immune Responses

…, A Minz-Dub, G Masrati, N Ben-Tal, A Savidor… - Plant …, 2017 - academic.oup.com
In search of Botrytis cinerea cell death-inducing proteins, we found a xyloglucanase (BcXYG1)
that induced strong necrosis and a resistance response in dicot plants. Expression of the …