Throughout life, individuals learn to predict a punishment via its association with sensory
stimuli. This process ultimately prompts goal-directed actions to prevent the danger, a behavior …

Weighing alternatives during reward pursuit is a vital cognitive computation that, when
disrupted by stress, yields aspects of neuropsychiatric disorders. To examine the neural …

Depression is a highly heterogeneous disease characterized by symptoms spanning from
anhedonia and behavioral despair to social withdrawal and learning deficit. Such diversity of …

Excitatory synaptic transmission in the lateral habenula (LHb), an evolutionarily ancient
subcortical structure, encodes aversive stimuli and affective states. Habenular glutamatergic …

Spontaneous network activity shapes emerging neuronal circuits during early brain development
prior to sensory perception. However, how neuromodulation influences this activity is …

Animals can cope with isolated stressful situations without enduring long‐term consequences.
However, when exposure to stressors becomes recurrent, behavioural symptoms of …

Lateral habenula ( LH b) hyperactivity plays a pivotal role in the emergence of negative
emotional states, including those occurring during withdrawal from addictive drugs. We have …

Dopamine release guides reward encoding, but the contribution of glutamate remains
unclear. In this issue of Neuron, Zell et al. leverage the genetic ablation of dopamine synthesis …

… deux frères, Alvaro Pérez et surtout Nuno Pérez, jouaient également un rôle important. C’est
le premier quart du XIIIe siècle qui constitue l’apogée des Lara, avec la tutelle exercée par …

… The king’s close contact with Nuno Perez probably also introduced him, at a young age,
to Count Nuno’s sons, Fernando, Alvaro, and Gonzalo Nunez. The oldest of them, Fernando, …