Many traditional pharmacopeias include Aristolochia and related plants, which contain
nephrotoxins and mutagens in the form of aristolochic acids and similar compounds (collectively, …

Somatic mutations in cancer genomes are caused by multiple mutational processes each of
which generates a characteristic mutational signature. Using 84,729,690 somatic mutations …

Cisplatin reacts with DNA and thereby likely generates a characteristic pattern of somatic
mutations, called a mutational signature. Despite widespread use of cisplatin in cancer …

Humans are frequently exposed to acrylamide, a probable human carcinogen found in
commonplace sources such as most heated starchy foods or tobacco smoke. Prior evidence has …

Mutational signatures can reveal the history of mutagenic processes that cells were exposed
to before and during tumorigenesis. We expect that as-yet-undiscovered mutational …

Protein binding microarrays provide comprehensive information about the DNA binding
specificities of transcription factors (TFs), and can be used to quantitatively predict the effects of …

Study of mutational signatures in cancers can reveal the history of mutagenic processes that
cells were exposed to prior and during tumourigenesis. Although recent work has identified …

… Although quantitative measurement of surface coverage percentages of the PEBAX layer
were unavailable for this study, it is apparent from the IR and AFM data that the 1 wt.% PEBAX …

Acrylamide, a probable human carcinogen, is ubiquitously present in the human environment,
with sources including heated starchy foods, coffee and cigarette smoke. Humans are …

The bacterial pathogen Xanthomonas campestris pv. campestris co‐ordinates virulence
factor production and biofilm dispersal through a diffusible signal factor (DSF)‐mediated cell–…