Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells

HG Asenjo, A Gallardo, L López-Onieva, I Tejada… - Science …, 2020 - science.org
When self-renewing pluripotent cells receive a differentiation signal, ongoing cell
duplication needs to be coordinated with entry into a differentiation program. Accordingly, …

[HTML][HTML] The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malignant transformation

…, R Montes, A Garcia-Moreno, A Gallardo… - Cell Death & …, 2023 - nature.com
Pediatric Acute Myeloid Leukemia (AML) is a rare and heterogeneous disease characterized
by a high prevalence of gene fusions as driver mutations. Despite the improvement of …

EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization

A Gallardo, A Molina, HG Asenjo, L Lopez-Onieva… - Oncogene, 2022 - nature.com
Reversible transition between the epithelial and mesenchymal states are key aspects of
carcinoma cell dissemination and the metastatic disease, and thus, characterizing the molecular …

[HTML][HTML] Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells

…, L Lopez-Onieva, A Gallardo… - Nature …, 2023 - nature.com
The potential of pluripotent cells to respond to developmental cues and trigger cell
differentiation is enhanced during the G1 phase of the cell cycle, but the molecular mechanisms …

The molecular clock protein Bmal1 regulates cell differentiation in mouse embryonic stem cells

A Gallardo, A Molina, HG Asenjo… - Life Science …, 2020 - life-science-alliance.org
Mammals optimize their physiology to the light–dark cycle by synchronization of the master
circadian clock in the brain with peripheral clocks in the rest of the tissues of the body. …

EZH2 endorses cell plasticity to carcinoma cells facilitating mesenchymal to epithelial transition and tumour colonization

A Gallardo, A Molina, HG Asenjo, L Lopez-Onieva… - bioRxiv, 2022 - biorxiv.org
Reversible transition between the epithelial and mesenchymal states are key aspects of
carcinoma cell dissemination and the metastatic disease, and thus, characterizing the molecular …

Influence of the structure on the electrochemical performance of lithium transition metal phosphates as cathodic materials in rechargeable lithium batteries: a new high …

…, J Garcia-Jaca, JM Gallardo-Amores… - Chemistry of …, 2001 - ACS Publications
Materials built from MO 6 octahedra linked to XO 4 tetrahedra are good candidates for
studying the different factors that determine the electrode potential. Among them, olivine-like …

Serum Galactomannan Versus a Combination of Galactomannan and Polymerase Chain Reaction–Based Aspergillus DNA Detection for Early Therapy of Invasive …

…, JT Silva, M Batlle, C Solano, D Gallardo… - Clinical Infectious …, 2015 - academic.oup.com
Background. The benefit of the combination of serum galactomannan (GM) assay and
polymerase chain reaction (PCR)–based detection of serum Aspergillus DNA for the early …

Lattice Dynamics of β-V2O5: Raman Spectroscopic Insight into the Atomistic Structure of a High-Pressure Vanadium Pentoxide Polymorph

…, JM Gallardo-Amores, U Amador… - Inorganic …, 2012 - ACS Publications
We report here the Raman spectrum and lattice dynamics study of a well-crystallized β-V 2
O 5 material prepared via a high-temperature/high-pressure (HT/HP) route, using α-V 2 O 5 …

EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells

A Gallardo, L López-Onieva, E Belmonte-Reche… - bioRxiv, 2023 - biorxiv.org
Emerging studies support that the Polycomb Repressive Complex 2 (PRC2) regulates
phenotypic changes of carcinoma cells by modulating their shifts among metastable states within …