User profiles for Amanda J. Lea
Amanda J. LeaVanderbilt University Verified email at vanderbilt.edu Cited by 1878 |
Genome-wide quantification of the effects of DNA methylation on human gene regulation
10.7554/eLife.37513.001 Changes in DNA methylation are involved in development, disease,
and the response to environmental conditions. However, not all regulatory elements are …
and the response to environmental conditions. However, not all regulatory elements are …
High social status males experience accelerated epigenetic aging in wild baboons
Aging, for virtually all life, is inescapable. However, within populations, biological aging
rates vary. Understanding sources of variation in this process is central to understanding the …
rates vary. Understanding sources of variation in this process is central to understanding the …
Developmental plasticity: bridging research in evolution and human health
Early life experiences can have profound and persistent effects on traits expressed throughout
the life course, with consequences for later life behavior, disease risk, and mortality rates. …
the life course, with consequences for later life behavior, disease risk, and mortality rates. …
Urbanization and market integration have strong, nonlinear effects on cardiometabolic health in the Turkana
The “mismatch” between evolved human physiology and Western lifestyles is thought to
explain the current epidemic of cardiovascular disease (CVD) in industrialized societies. …
explain the current epidemic of cardiovascular disease (CVD) in industrialized societies. …
[HTML][HTML] A flexible, efficient binomial mixed model for identifying differential DNA methylation in bisulfite sequencing data
Identifying sources of variation in DNA methylation levels is important for understanding gene
regulation. Recently, bisulfite sequencing has become a popular tool for investigating DNA …
regulation. Recently, bisulfite sequencing has become a popular tool for investigating DNA …
Heritable victimization and the benefits of agonistic relationships
Here, we present estimates of heritability and selection on network traits in a single
population, allowing us to address the evolutionary potential of social behavior and the poorly …
population, allowing us to address the evolutionary potential of social behavior and the poorly …
Resource base influences genome‐wide DNA methylation levels in wild baboons (Papio cynocephalus)
Variation in resource availability commonly exerts strong effects on fitness‐related traits in
wild animals. However, we know little about the molecular mechanisms that mediate these …
wild animals. However, we know little about the molecular mechanisms that mediate these …
Developmental constraints in a wild primate
AJ Lea, J Altmann, SC Alberts… - The American …, 2015 - journals.uchicago.edu
Early-life experiences can dramatically affect adult traits. However, the evolutionary origins
of such early-life effects are debated. The predictive adaptive response hypothesis argues …
of such early-life effects are debated. The predictive adaptive response hypothesis argues …
Heterospecific eavesdropping in a nonsocial species
Many species respond to heterospecific alarm calls, and the majority are social taxa and
possess complex alarm calls themselves. Thus, the ability to respond to heterospecific alarm …
possess complex alarm calls themselves. Thus, the ability to respond to heterospecific alarm …
Complex sources of variance in female dominance rank in a nepotistic society
AJ Lea, NH Learn, MJ Theus, J Altmann, SC Alberts - Animal behaviour, 2014 - Elsevier
Many mammalian societies are structured by dominance hierarchies, and an individual's
position within this hierarchy can influence reproduction, behaviour, physiology and health. In …
position within this hierarchy can influence reproduction, behaviour, physiology and health. In …