We conducted the largest investigation of predisposition variants in cancer to date, discovering
853 pathogenic or likely pathogenic variants in 8% of 10,389 cases from 33 cancer types. …

Genotype-phenotype relationships shape health and population fitness but remain difficult
to predict and interpret. Here, we apply an evolutionary action method to de novo missense …

Objective To examine the associations of maternal self-efficacy (MSE) and perceived social
support with parenting stress during the postpartum period during the COVID-19 pandemic …

Liver cancer has the second highest worldwide cancer mortality rate and has limited
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole-exome …

Purpose During the COVID-19 pandemic, many universities evacuated their campuses,
requiring students to vacate on campus residences. The psychological outcomes of students …

Genome‐wide association studies (GWAS) and whole‐exome sequencing (WES) generate
massive amounts of genomic variant information, and a major challenge is to identify which …

Certain mutations can cause proteins to accumulate in neurons, leading to neurodegeneration.
We recently showed, however, that upregulation of a wild-type protein, Ataxin1, caused …

Purpose This study examined the rates of unexpected birth experiences due to the COVID-19
pandemic and its association with women’s postpartum mental health symptoms (…

Context Elucidating the genomic landscape of sporadic parathyroid carcinoma (PC) has
been limited by low tumor incidence. Objective Identify driver mutations of sporadic PC and …

Prenatal generalized anxiety disorder (GAD) is a common and underdiagnosed condition with
negative health consequences to both the pregnant individual and child. Here we studied …