Codiversification of gut microbiota with humans
The gut microbiomes of human populations worldwide have many core microbial species in
common. However, within a species, some strains can show remarkable population …
common. However, within a species, some strains can show remarkable population …
Gut microbiota has a widespread and modifiable effect on host gene regulation
Variation in gut microbiome is associated with wellness and disease in humans, and yet the
molecular mechanisms by which this variation affects the host are not well understood. A …
molecular mechanisms by which this variation affects the host are not well understood. A …
Microbial control of host gene regulation and the evolution of host–microbiome interactions in primates
L Grieneisen, AL Muehlbauer… - … Transactions of the …, 2020 - royalsocietypublishing.org
Recent comparative studies have found evidence consistent with the action of natural
selection on gene regulation across primate species. Other recent work has shown that the …
selection on gene regulation across primate species. Other recent work has shown that the …
[PDF][PDF] Interspecies variation in hominid gut microbiota controls host gene regulation
The gut microbiome exhibits extreme compositional variation between hominid hosts. However,
it is unclear how this variation impacts host physiology across species and whether this …
it is unclear how this variation impacts host physiology across species and whether this …
Quantitative trait loci (QTL)-guided metabolic engineering of a complex trait
…, D Pinel, S Bauer, AL Muehlbauer… - ACS Synthetic …, 2017 - ACS Publications
Engineering complex phenotypes for industrial and synthetic biology applications is difficult
and often confounds rational design. Bioethanol production from lignocellulosic feedstocks …
and often confounds rational design. Bioethanol production from lignocellulosic feedstocks …
Untangling the dynamics of host-microbiome interactions
AL Muehlbauer - 2022 - search.proquest.com
The gut microbiome performs numerous important functions for the host and has been
closely linked to the development of certain diseases. Extreme variation in gut microbiome …
closely linked to the development of certain diseases. Extreme variation in gut microbiome …
Variation in gut microbiota composition impacts host gene expression
Variation in gut microbiome is associated with wellness and disease in humans, yet the
molecular mechanisms by which this variation affects the host are not well understood. A likely …
molecular mechanisms by which this variation affects the host are not well understood. A likely …
QTL-guided metabolic engineering of a complex trait
…, L Sutardja, D Pinel, S Bauer, AL Muehlbauer… - bioRxiv, 2016 - biorxiv.org
Engineering complex phenotypes for industrial and synthetic biology applications is difficult
and often confounds rational design. Bioethanol production from lignocellulosic feedstocks …
and often confounds rational design. Bioethanol production from lignocellulosic feedstocks …
[HTML][HTML] Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine …
…, RD Stevens, O Ilkayeva, T George, MJ Muehlbauer… - Molecular …, 2016 - Elsevier
Objective A branched-chain amino acid (BCAA)-related metabolic signature is strongly
associated with insulin resistance and predictive of incident diabetes and intervention outcomes. …
associated with insulin resistance and predictive of incident diabetes and intervention outcomes. …
Glycogen synthase kinase 3β inhibitors induce apoptosis in ovarian cancer cells and inhibit in-vivo tumor growth
TS Hilliard, IN Gaisina, AG Muehlbauer… - Anti-cancer …, 2011 - journals.lww.com
Ovarian cancer is the most lethal gynecological malignancy among US women. Paclitaxel/carboplatin
is the current drug therapy used to treat ovarian cancer, but most women develop …
is the current drug therapy used to treat ovarian cancer, but most women develop …