[HTML][HTML] Aerosol infection of Balb/c mice with eastern equine encephalitis virus; susceptibility and lethality

AL Phelps, LM O'Brien, LS Eastaugh, C Davies… - Virology journal, 2019 - Springer
Background Eastern equine encephalitis virus is an alphavirus that naturally cycles between
mosquitoes and birds or rodents in Eastern States of the US. Equine infection occurs by …

A recombinant humanized monoclonal antibody completely protects mice against lethal challenge with Venezuelan equine encephalitis virus

WG Hu, AL Phelps, S Jager, D Chau, CC Hu… - Vaccine, 2010 - Elsevier
A recombinant humanized antibody to Venezuelan equine encephalitis virus (VEEV) was
constructed in a monocistronic adenoviral expression vector with a foot-and-mouth-disease …

[HTML][HTML] Aerosol Survival, Disinfection and Formalin Inactivation of Nipah Virus

SJ Smither, LS Eastaugh, LM O'Brien, AL Phelps… - Viruses, 2022 - mdpi.com
Nipah virus is a relatively newly discovered emerging virus on the WHO list of priority
pathogens which has the potential to cause outbreaks with high fatality rates. Whilst progress is …

[HTML][HTML] Evaluation of the SARS-CoV-2 inactivation efficacy associated with buffers from three kits used on high-throughput RNA extraction platforms

…, JS Findlay, SJ Smither, AL Phelps… - Frontiers in Cellular …, 2021 - frontiersin.org
Rapid and demonstrable inactivation of SARS-CoV-2 is crucial to ensure operator safety during
high-throughput testing of clinical samples. The inactivation efficacy of SARS-CoV-2 was …

[HTML][HTML] Tumour Necrosis Factor-α, Chemokines, and Leukocyte Infiltrate Are Biomarkers for Pathology in the Brains of Venezuelan Equine Encephalitis (VEEV) …

AL Phelps, FJ Salguero, L Hunter, AL Stoll, DC Jenner… - Viruses, 2023 - mdpi.com
Venezuelan equine encephalitis virus (VEEV) is a disease typically confined to South and
Central America, whereby human disease is characterised by a transient systemic infection …

[HTML][HTML] Susceptibility and lethality of western equine encephalitis virus in balb/c mice when infected by the aerosol route

AL Phelps, LM O'Brien, LS Eastaugh, C Davies… - Viruses, 2017 - mdpi.com
Western equine encephalitis virus (WEEV) naturally cycles between mosquitos and birds or
rodents, with a case fatality rate of up to 15% in humans during epizootic outbreaks. There …

[HTML][HTML] Development of a novel monoclonal antibody with reactivity to a wide range of Venezuelan equine encephalitis virus strains

…, CD Underwood-Fowler, SA Goodchild, AL Phelps… - Virology Journal, 2009 - Springer
Background There is currently a requirement for antiviral therapies capable of protecting
against infection with Venezuelan equine encephalitis virus (VEEV), as a licensed vaccine is …

Assessment of antimicrobial peptide LL-37 as a post-exposure therapy to protect against respiratory tularemia in mice

…, MI Richards, DC Jenner, TR Laws, AL Phelps… - Peptides, 2013 - Elsevier
Early activation of the innate immune response is important for protection against infection
with Francisella tularensis live vaccine strain (LVS) in mice. The human cathelicidin …

[HTML][HTML] Cross-Strain Neutralizing and Protective Monoclonal Antibodies against EEEV or WEEV

AL Phelps, LM O'Brien, DO Ulaeto, FW Holtsberg… - Viruses, 2021 - mdpi.com
The three encephalitic alphaviruses, namely, the Venezuelan, eastern, and western equine
encephalitis viruses (VEEV, EEEV, and WEEV), are classified by the Centers for Disease …

Investigative study into whether an insect repellent has virucidal activity against SARS-CoV-2

…, S Notman, LM O'Brien, AL Phelps… - Journal of General …, 2021 - microbiologyresearch.org
A small-scale study with Mosi-guard Natural spray, an insect repellent containing Citriodiol,
was performed to determine if it has virucidal activity against SARS-CoV-2. A liquid test …