User profiles for Amanda M. Larracuente

Amanda Larracuente

University of Rochester
Verified email at bio.rochester.edu
Cited by 4883

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, VN Iyer, DA Pollard, TB Sackton, AM Larracuente… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Genetics on the Fly: A Primer on the Drosophila Model System

KG Hales, CA Korey, AM Larracuente, DM Roberts - Genetics, 2015 - academic.oup.com
Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them a …

The ecology and evolutionary dynamics of meiotic drive

…, U Knief, H Kokko, AM Larracuente… - Trends in ecology & …, 2016 - cell.com
Meiotic drivers are genetic variants that selfishly manipulate the production of gametes to
increase their own rate of transmission, often to the detriment of the rest of the genome and the …

Evolution of protein-coding genes in Drosophila

AM Larracuente, TB Sackton, AJ Greenberg, A Wong… - Trends in Genetics, 2008 - cell.com
Several contributing factors have been implicated in evolutionary rate heterogeneity among
proteins, but their evolutionary mechanisms remain poorly characterized. The recently …

The Selfish Segregation Distorter Gene Complex of Drosophila melanogaster

AM Larracuente, DC Presgraves - Genetics, 2012 - academic.oup.com
Segregation Distorter (SD) is an autosomal meiotic drive gene complex found worldwide in
natural populations of Drosophila melanogaster. During spermatogenesis, SD induces …

[HTML][HTML] Islands of retroelements are major components of Drosophila centromeres

…, J Erceg, BJ Beliveau, CT Wu, AM Larracuente… - PLoS …, 2019 - journals.plos.org
Centromeres are essential chromosomal regions that mediate kinetochore assembly and
spindle attachments during cell division. Despite their functional conservation, centromeres are …

Long reads are revolutionizing 20 years of insect genome sequencing

…, A Powell, AM Larracuente… - Genome biology and …, 2021 - academic.oup.com
The first insect genome assembly (Drosophila melanogaster) was published two decades
ago. Today, nuclear genome assemblies are available for a staggering 601 insect species …

Firefly genomes illuminate parallel origins of bioluminescence in beetles

…, SM Lewis, S Shigenobu, SM Bybee, AM Larracuente… - elife, 2018 - elifesciences.org
10.7554/eLife.36495.001 Fireflies and their luminous courtships have inspired centuries of
scientific study. Today firefly luciferase is widely used in biotechnology, but the evolutionary …

Analyses of 600+ insect genomes reveal repetitive element dynamics and highlight biodiversity-scale repeat annotation challenges

…, A Powell, D Marshall, AM Larracuente… - Genome …, 2023 - genome.cshlp.org
Repetitive elements (REs) are integral to the composition, structure, and function of eukaryotic
genomes, yet remain understudied in most taxonomic groups. We investigated REs …

Heterochromatin-Enriched Assemblies Reveal the Sequence and Organization of the Drosophila melanogaster Y Chromosome

CH Chang, AM Larracuente - Genetics, 2019 - academic.oup.com
Heterochromatic repeat-rich regions are often missing from even the best genome
assemblies. Chang and Larracuente designed a de novo assembly strategy to improve the …