The focus of this article is criminal drug users and their changing behavior. Two important
considerations are addressed within this topic. First, an overview of drug use is given, …

Objectives Children with congenital esophageal atresia with tracheoesophageal fistula (TEF)
require complex medical and surgical care, but few guidelines exist to guide the long term …

Objective This study exploits the intersection between molecular-targeted therapies and
immune-checkpoint inhibition to define new means to treat pancreatic cancer. Design Patient-…

Objectives/Hypothesis The purpose of this investigation was to assess current drug‐induced
sleep endoscopy (DISE) practice patterns at centers that have published on the technique, …

Study Objectives: Obstructive sleep apnea (OSA) is common in children with Down
syndrome (DS) and associated with significant morbidity. In the current study we examined …

Pancreatic ductal adenocarcinoma (PDAC), like many KRAS-driven tumors, preferentially
loses CDKN2A that encodes an endogenous CDK4/6 inhibitor to bypass the RB-mediated cell …

Cancer biology is influenced by the tumor microenvironment, which impacts disease prognosis
and therapeutic interventions. The inter-relationship of tumor-infiltrating lymphocytes, …

Effective vaccination against coronavirus mitigates the risk of hospitalisation and mortality;
however, it is unclear whether vaccination status influences long COVID symptoms in patients …

Non-secretor status due to homozygosity for the common FUT2 variant c.461G>A (p.Trp154
∗ ) is associated with either risk for autoimmune diseases or protection against viral diarrhea …

Objectives/Hypothesis The Aerodigestive Program (the Aero Program) at Children's Hospital
Colorado is a multidisciplinary program focused on airway, digestive, and lung disorders in …