A thousand miles up the Nile

AB Edwards - … -Century Travels, Explorations and Empires, Part II …, 2021 - taylorfrancis.com
Amelia Ann Blanford Edwards (1831-92) was born in London to a barrister's daughter and an
army officer. She was taught at home, mainly by her mother, and flourished in literature and…

A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

D Lin, AS Edwards, JP Fawcett, G Mbamalu… - Nature cell …, 2000 - nature.com
Cellular asymmetry is critical for the development of multicellular organisms. Here we show
that homologues of proteins necessary for asymmetric cell division in Caenorhabditis …

[PDF][PDF] Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

J Delile, T Rayon, M Melchionda, A Edwards… - …, 2019 - journals.biologists.com
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural
tube determines the identity of neural progenitors and the function and physiology of the …

[BOOK][B] A Thousand Miles Up the Nile: Fully Illustrated Second Edition

AB Edwards - 2008 - books.google.com
As enthralling as any work of fiction, A Thousand Miles up the Nile is the quintessential
Victorian travel book. In 1873, Amelia B. Edwards, an upper-class Victorian spinster, spent the …

[HTML][HTML] Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

…, A Dibbs, J Diring, PC Driscoll, C Earl, A Edwards… - The Lancet, 2020 - thelancet.com
To evaluate these risks, we enrolled 200 patient-facing HCWs between March 26 and April 8,
2020, in SARS-CoV-2 Acquisition in Frontline Healthcare Workers—Evaluation to inform …

A-kinase anchoring proteins: protein kinase A and beyond

AS Edwards, JD Scott - Current opinion in cell biology, 2000 - Elsevier
Compartmentalization of kinases and phosphatases is a key determinant in the specificity of
second messenger mediated signaling events. Localization of the cAMP-dependent protein …

[PDF][PDF] Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population

…, ZB Gaber, SHL Austin, M del Mar Masdeu, A Edwards… - Cell stem cell, 2021 - cell.com
Neural stem cell numbers fall rapidly in the hippocampus of juvenile mice but stabilize during
adulthood, ensuring lifelong hippocampal neurogenesis. We show that this stabilization of …

[HTML][HTML] Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C

AS Edwards, AC Newton - Journal of biological chemistry, 1997 - ASBMB
Mature protein kinase C is phosphorylated at a conserved carboxyl-terminal motif that contains
a Ser (or Thr) bracketed by two hydrophobic residues; in protein kinase C βII, this residue …

[HTML][HTML] Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C βII

AS Edwards, MC Faux, JD Scott, AC Newton - Journal of Biological …, 1999 - ASBMB
Protein kinase C is processed by three phosphorylation events before it is competent to
respond to second messengers. Specifically, the enzyme is first phosphorylated at the activation …

[PDF][PDF] GATA3 mediates a fast, irreversible commitment to BMP4-driven differentiation in human embryonic stem cells

…, B Gharibi, RSM Sheriff, A Maity, YF Wang, A Edwards… - Cell stem cell, 2020 - cell.com
During early development, extrinsic triggers prompt pluripotent cells to begin the process of
differentiation. When and how human embryonic stem cells (hESCs) irreversibly commit to …