Genomic imprinting directs the allele-specific marking and expression of loci according to
their parental origin. Differential DNA methylation at imprinted control regions (ICRs) is …

T cell receptor (TCR) signals can elicit full activation with acquisition of effector functions or
a state of anergy. Here, we ask whether microRNAs affect the interpretation of TCR signaling. …

Epigenetic information is transmitted from mother to daughter cells through mitosis. Here, to
identify factors that might play a role in conveying epigenetic memory through cell division, …

Jarid2 is part of the Polycomb Repressor complex 2 (PRC2) responsible for genome-wide
H3K27me3 deposition. Unlike other PRC2-deficient embryonic stem cells (ESCs), however, …

Imprinted genes are regulated according to parental origin and can influence embryonic
growth and metabolism and confer disease susceptibility. Here, we designed sensitive allele-…

Pds5 and Wpl1 act as anti‐establishment factors preventing sister‐chromatid cohesion until
counteracted in S‐phase by the cohesin acetyl‐transferase Eso1. However, Pds5 is also …

In budding yeast and humans, cohesion establishment during S phase requires the
acetyltransferase Eco1/Esco1-2, which acetylates the cohesin subunit Smc3 on two conserved …

Genomic imprinting is an epigenetically mediated mechanism that regulates allelic expression
of genes based upon parent-of-origin and provides a paradigm for studying epigenetic …

Cohesin has essential roles in chromosome structure, segregation and repair. Cohesin binding
to chromosomes is catalyzed by the cohesin loader, Mis4 in fission yeast. How cells fine …

Epigenetic information is transmitted from mother to daughter cells through mitosis. To
identify trans-acting factors and cis-acting elements that might be important for conveying …