User profiles for Amir Ata Saei

Amir Ata Saei

Assistant professor at Karolinska Institutet
Verified email at ki.se
Cited by 3200

Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges

S Laurent, AA Saei, S Behzadi… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Bearing in mind that many promising drug candidates have the problem of
reaching their target site, the concept of advanced drug delivery can play a significant …

Targeted superparamagnetic iron oxide nanoparticles for early detection of cancer: Possibilities and challenges

Z Bakhtiary, AA Saei, MJ Hajipour, M Raoufi… - … , Biology and Medicine, 2016 - Elsevier
Nanomedicine, the integration of nanotechnological tools in medicine demonstrated promising
potential to revolutionize the diagnosis and treatment of various human health conditions. …

Electrochemical biosensors for glucose based on metal nanoparticles

AA Saei, JEN Dolatabadi, P Najafi-Marandi… - TrAC Trends in …, 2013 - Elsevier
Nanotechnology has affected almost all aspects of biomedicine. The integration of
nanomaterials has contributed to the selectivity, the versatility, the stability and especially the …

Theranostic MUC-1 aptamer targeted gold coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging and photothermal therapy of colon …

M Azhdarzadeh, F Atyabi, AA Saei… - Colloids and Surfaces B …, 2016 - Elsevier
Favorable physiochemical properties and the capability to accommodate targeting moieties
make superparamegnetic iron oxide nanoparticles (SPIONs) popular theranostic agents. In …

Superparamagnetic iron oxide nanoparticles for in vivo molecular and cellular imaging

…, S Laurent, F Atyabi, AA Saei… - Contrast media & …, 2015 - Wiley Online Library
In the last decade, the biomedical applications of nanoparticles (NPs) (eg cell tracking,
biosensing, magnetic resonance imaging (MRI), targeted drug delivery, and tissue engineering) …

Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug

X Zhang, K Selvaraju, AA Saei, P D'Arcy, RA Zubarev… - Biochimie, 2019 - Elsevier
Auranofin is a gold (I)-containing compound used for the treatment of rheumatic arthritis.
Auranofin has anticancer activity in animal models and is approved for clinical trials for lung and …

[HTML][HTML] Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities

…, H Gharibi, E Voke, MP Landry, AA Saei… - Nature …, 2022 - nature.com
Robust characterization of the protein corona—the layer of proteins that spontaneously forms
on the surface of nanoparticles immersed in biological fluids—is vital for prediction of the …

Microparticles containing erlotinib-loaded solid lipid nanoparticles for treatment of non-small cell lung cancer

Z Bakhtiary, J Barar, A Aghanejad, AA Saei… - Drug development …, 2017 - Taylor & Francis
Non-small cell lung cancer (NSCLC) patients with sensitizing mutations in the exons 18–21
of the epithelial growth factor receptor (EGFR) gene show increased kinase activity of EGFR. …

Nanoparticle surface functionality dictates cellular and systemic toxicity

AA Saei, M Yazdani, SE Lohse, Z Bakhtiary… - Chemistry of …, 2017 - ACS Publications
Engineered nanoparticles (NPs) have opened new frontiers in therapeutics and diagnostics
in recent years. The surface functionality of these nanoparticles often predominates their …

Nanotoxicology: advances and pitfalls in research methodology

M Azhdarzadeh, AA Saei, S Sharifi, MJ Hajipour… - …, 2015 - Future Medicine
As research progresses, nanoparticles (NPs) are becoming increasingly promising tools for
medical diagnostics and therapeutics. Despite this rise, their potential risks to human health, …