Optical imaging of cortical activity offers several advantages over conventional
electrophysiological and anatomical techniques. One can map a relatively large region, obtain …

Modern neuroimaging techniques use signals originating from microcirculation to map brain
function. In this study, activity-dependent changes in oxyhemoglobin, deoxyhemoglobin, …

THE mammalian cortex is organized in a columnar fashion: neurons lying below each other
from the pia to the white matter usually share many functional properties. Across the cortical …

A high spatial resolution optical imaging system was developed to visualize cerebral cortical
activity in vivo. This method is based on activity-dependent intrinsic signals and does not …

Evoked activity in the mammalian cortex and the resulting behavioral responses exhibit a
large variability to repeated presentations of the same stimulus. This study examined whether …

We have shown previously the existence of small, activity-dependent changes in intrinsic
optical properties of cortex that are useful for optical imaging of cortical functional architecture. …

Spontaneous cortical activity—ongoing activity in the absence of intentional sensory input—has
been studied extensively 1 , using methods ranging from EEG (electroencephalography) …

Analysis of fluorescence decay kinetics aims at the determination of the analytic expression
and the numerical values of the pertinent parameters which describe the decay process. In …

The relation between the activity of a single neocortical neuron and the dynamics of the
network in which it is embedded was explored by single-unit recordings and real-time optical …

The rodent primary somatosensory cortex is spontaneously active in the form of locally
synchronous membrane depolarizations (UP states) separated by quiescent hyperpolarized …