Importance The evidence for benefit of convalescent plasma for critically ill patients with
COVID-19 is inconclusive. Objective To determine whether convalescent plasma would improve …

Introduction Localised infections, and burn wound sepsis are key concerns in the treatment
of burns patients, and prevention of colonisation largely relies on biocides. Acetic acid has …

Objective: The aim of this study was to measure neutrophil function longitudinally following
burn injury and to examine the relationship between neutrophil dysfunction and sepsis. …

Objectives Pseudomonas aeruginosa is a common nosocomial pathogen responsible for
significant morbidity and mortality internationally. Patients may become colonised or infected …

Importance Patients with septic shock undergo adrenergic stress, which affects cardiac,
immune, inflammatory, and metabolic pathways. β-Blockade may attenuate the adverse effects …

Among long-stay critically ill patients in the adult intensive care unit (ICU), there are often
marked changes in the complexity of the gut microbiota. However, it remains unclear whether …

Antimicrobial medicated dressings (AMD) are often used to reduce bacterial infection of burns
and other wounds. However, there is limited literature regarding comparative efficacies to …

Thermal imaging is a tool that can be used to determine burn depth. We have revisited the
use of this technology in the assessment of burns and aim to establish if high resolution, real-…

Background Research into the treatment of hypertrophic burn scar is hampered by the
variability and subjectivity of existing outcome measures. This study aims to measure the inter- …

Objective: The Birmingham Burn Centre has continued to publish mortality data over the last
65 years. It is one of the longest running cross-sectional cohort studies in the world. We …