[HTML][HTML] The amphioxus genome and the evolution of the chordate karyotype

…, JJ Gibson-Brown, IV Grigoriev, AC Horton… - Nature, 2008 - nature.com
Lancelets (‘amphioxus’) are the modern survivors of an ancient chordate lineage, with a
fossil record dating back to the Cambrian period. Here we describe the structure and gene …

Analysis of the small GTPase gene superfamily of Arabidopsis

V Vernoud, AC Horton, Z Yang, E Nielsen - Plant physiology, 2003 - academic.oup.com
Small GTP-binding proteins regulate diverse processes in eukaryotic cells such as signal
transduction, cell proliferation, cytoskeletal organization, and intracellular membrane trafficking…

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

RC Culverhouse, NL Saccone, AC Horton, Y Ma… - Molecular …, 2018 - nature.com
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …

Association between substance use disorder and polygenic liability to schizophrenia

SM Hartz, AC Horton, M Oehlert, CE Carey… - Biological …, 2017 - Elsevier
Background There are high levels of comorbidity between schizophrenia and substance
use disorder, but little is known about the genetic etiology of this comorbidity. Methods We …

Genetic correlation between smoking behaviors and schizophrenia

SM Hartz, AC Horton, DB Hancock, TB Baker… - Schizophrenia …, 2018 - Elsevier
Horton a , Dana B. Hancock b , Timothy B. Baker … Hartz, Horton and Bierut designed and
conducted statistical analyses. All authors contributed to data harmonization and interpretation …

Conservation of linkage and evolution of developmental function within the Tbx2/3/4/5 subfamily of T-box genes: implications for the origin of vertebrate limbs

AC Horton, NR Mahadevan, C Minguillon… - Development genes and …, 2008 - Springer
T-box genes encode a family of DNA-binding transcription factors implicated in numerous
developmental processes in all metazoans. The Tbx2/3/4/5 subfamily genes are especially …

Developmental expression of the amphioxus Tbx1/10 gene illuminates the evolution of vertebrate branchial arches and sclerotome

NR Mahadevan, AC Horton… - Development genes and …, 2004 - Springer
We have isolated an amphioxus T-box gene that is orthologous to the two vertebrate genes,
Tbx1 and Tbx10, and examined its expression pattern during embryonic and early larval …

Evolution of developmental functions by the Eomesodermin, T‐brain‐1, Tbx21 subfamily of T‐box genes: insights from amphioxus

AC Horton, JJ Gibson‐Brown - Journal of Experimental …, 2002 - Wiley Online Library
We have identified an amphioxus T‐box gene that is orthologous to the Eomesodermin, T‐brain‐1,
and Tbx21 genes of vertebrates, and we have characterized its expression pattern …

Phylogenetic analysis of new plant myosin sequences

M Bezanilla, AC Horton, HC Sevener… - Journal of molecular …, 2003 - Springer
We have sampled a large number of plant taxa, ranging from brown algae to angiosperms,
for the presence of myosin sequences. Using phylogenetic analysis, we show that all but two …

Phylogenetic analyses alone are insufficient to determine whether genome duplication (s) occurred during early vertebrate evolution

AC Horton, NR Mahadevan, I Ruvinsky… - … Zoology Part B …, 2003 - Wiley Online Library
The widely accepted notion that two whole‐genome duplications occurred during early
vertebrate evolution (the 2R hypothesis) stems from the fact that vertebrates often possess …