[HTML][HTML] The amphioxus genome and the evolution of the chordate karyotype
…, JJ Gibson-Brown, IV Grigoriev, AC Horton… - Nature, 2008 - nature.com
Lancelets (‘amphioxus’) are the modern survivors of an ancient chordate lineage, with a
fossil record dating back to the Cambrian period. Here we describe the structure and gene …
fossil record dating back to the Cambrian period. Here we describe the structure and gene …
Analysis of the small GTPase gene superfamily of Arabidopsis
Small GTP-binding proteins regulate diverse processes in eukaryotic cells such as signal
transduction, cell proliferation, cytoskeletal organization, and intracellular membrane trafficking…
transduction, cell proliferation, cytoskeletal organization, and intracellular membrane trafficking…
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
RC Culverhouse, NL Saccone, AC Horton, Y Ma… - Molecular …, 2018 - nature.com
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …
associated with increased risk of depression, but only in individuals exposed to stressful …
Association between substance use disorder and polygenic liability to schizophrenia
Background There are high levels of comorbidity between schizophrenia and substance
use disorder, but little is known about the genetic etiology of this comorbidity. Methods We …
use disorder, but little is known about the genetic etiology of this comorbidity. Methods We …
Genetic correlation between smoking behaviors and schizophrenia
SM Hartz, AC Horton, DB Hancock, TB Baker… - Schizophrenia …, 2018 - Elsevier
… Horton a , Dana B. Hancock b , Timothy B. Baker … Hartz, Horton and Bierut designed and
conducted statistical analyses. All authors contributed to data harmonization and interpretation …
conducted statistical analyses. All authors contributed to data harmonization and interpretation …
Conservation of linkage and evolution of developmental function within the Tbx2/3/4/5 subfamily of T-box genes: implications for the origin of vertebrate limbs
AC Horton, NR Mahadevan, C Minguillon… - Development genes and …, 2008 - Springer
T-box genes encode a family of DNA-binding transcription factors implicated in numerous
developmental processes in all metazoans. The Tbx2/3/4/5 subfamily genes are especially …
developmental processes in all metazoans. The Tbx2/3/4/5 subfamily genes are especially …
Developmental expression of the amphioxus Tbx1/10 gene illuminates the evolution of vertebrate branchial arches and sclerotome
NR Mahadevan, AC Horton… - Development genes and …, 2004 - Springer
We have isolated an amphioxus T-box gene that is orthologous to the two vertebrate genes,
Tbx1 and Tbx10, and examined its expression pattern during embryonic and early larval …
Tbx1 and Tbx10, and examined its expression pattern during embryonic and early larval …
Evolution of developmental functions by the Eomesodermin, T‐brain‐1, Tbx21 subfamily of T‐box genes: insights from amphioxus
AC Horton, JJ Gibson‐Brown - Journal of Experimental …, 2002 - Wiley Online Library
We have identified an amphioxus T‐box gene that is orthologous to the Eomesodermin, T‐brain‐1,
and Tbx21 genes of vertebrates, and we have characterized its expression pattern …
and Tbx21 genes of vertebrates, and we have characterized its expression pattern …
Phylogenetic analysis of new plant myosin sequences
M Bezanilla, AC Horton, HC Sevener… - Journal of molecular …, 2003 - Springer
We have sampled a large number of plant taxa, ranging from brown algae to angiosperms,
for the presence of myosin sequences. Using phylogenetic analysis, we show that all but two …
for the presence of myosin sequences. Using phylogenetic analysis, we show that all but two …
Phylogenetic analyses alone are insufficient to determine whether genome duplication (s) occurred during early vertebrate evolution
AC Horton, NR Mahadevan, I Ruvinsky… - … Zoology Part B …, 2003 - Wiley Online Library
The widely accepted notion that two whole‐genome duplications occurred during early
vertebrate evolution (the 2R hypothesis) stems from the fact that vertebrates often possess …
vertebrate evolution (the 2R hypothesis) stems from the fact that vertebrates often possess …