Sex is a modulator of health that has been historically overlooked in biomedical research.
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …

Sex differences exist in the incidence and presentation of many pregnancy complications,
including but not limited to pregnancy loss, spontaneous preterm birth, and fetal growth …

Background Human placental DNA methylation (DNAme) data is a valuable resource for
studying sex differences during gestation, as DNAme profiles after delivery reflect the …

Background Many human disease phenotypes manifest differently by sex, making the
development of methods for incorporating X and Y-chromosome data into analyses vital. …

Selective serotonin reuptake inhibitors (SSRIs) for treatment of prenatal maternal depression
have been associated with neonatal neurobehavioral disturbances, though the molecular …

Background: Alzheimer’s disease (AD) disproportionately affects females with steeper cognitive
decline and more neuropathology compared to males, which is exacerbated in females …

Background Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina
Infinium Methylation bead arrays is often used to explore the connections between in utero …

Background Understanding the molecular basis of susceptibility factors to the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It is …

Sex differences are a robust finding in many areas of adult health, including cardiovascular
disease, psychiatric disorders, and chronic pain. However, many sex differences are not …

Many pregnancy disorders, including early-onset preeclampsia (EOPE), are associated with
defects in placental trophoblast cell invasion and differentiation during early placental …