ChAMP: updated methylation analysis pipeline for Illumina BeadChips
The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput
DNA methylation analysis, effectively doubling the coverage compared to the older 450 …
DNA methylation analysis, effectively doubling the coverage compared to the older 450 …
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats
S Iyengar, AA Webster, SK Hemrick-Luecke… - … of Pharmacology and …, 2004 - ASPET
5-Hydroxytryptamine (serotonin) (5-HT) and norepinephrine (NE) are implicated in modulating
descending inhibitory pain pathways in the central nervous system. Duloxetine is a …
descending inhibitory pain pathways in the central nervous system. Duloxetine is a …
Systematic review of changes and recovery in physical function and fitness after severe acute respiratory syndrome–related coronavirus infection: implications for …
S Rooney, A Webster, L Paul - Physical therapy, 2020 - academic.oup.com
Objective This review sought to (1) compare physical function and fitness outcomes in people
infected with Severe Acute Respiratory Syndrome-related Coronavirus (SARS-CoV) with …
infected with Severe Acute Respiratory Syndrome-related Coronavirus (SARS-CoV) with …
Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans
Across diverse taxa, selfing species have evolved independently from outcrossing species
thousands of times. The transition from outcrossing to selfing decreases the effective …
thousands of times. The transition from outcrossing to selfing decreases the effective …
A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix
Aim: An outstanding challenge in epigenome studies is the estimation of cell-type proportions
in complex epithelial tissues. Materials & methods: Here, we construct and validate a DNA …
in complex epithelial tissues. Materials & methods: Here, we construct and validate a DNA …
Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats
RMA Simmons, AA Webster, AB Kalra… - Pharmacology …, 2002 - Elsevier
The involvement of Group II metabotropic receptors in acute and persistent pain states was
evaluated in several in vivo models of pain with selective and potent Group II metabotropic …
evaluated in several in vivo models of pain with selective and potent Group II metabotropic …
[HTML][HTML] Conscientious objection to abortion, the law and its implementation in Victoria, Australia: perspectives of abortion service providers
Background In Victoria, Australia, the law regulating abortion was reformed in 2008, and a
clause (‘Section 8’) was introduced requiring doctors with a conscientious objection to …
clause (‘Section 8’) was introduced requiring doctors with a conscientious objection to …
[PDF][PDF] Undifferentiated sarcomas develop through distinct evolutionary pathways
Undifferentiated sarcomas (USARCs) of adults are diverse, rare, and aggressive soft tissue
cancers. Recent sequencing efforts have confirmed that USARCs exhibit one of the highest …
cancers. Recent sequencing efforts have confirmed that USARCs exhibit one of the highest …
[HTML][HTML] Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins
Background Rheumatoid arthritis is a common autoimmune disorder influenced by both
genetic and environmental factors. Epigenome-wide association studies can identify …
genetic and environmental factors. Epigenome-wide association studies can identify …
daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
10.7554/eLife.30057.001 daf-16/FoxO is required to survive starvation in Caenorhabditis
elegans, but how daf-16IFoxO promotes starvation resistance is unclear. We show that daf-16/…
elegans, but how daf-16IFoxO promotes starvation resistance is unclear. We show that daf-16/…