Custom-designed, degradation-resistant messenger RNAs in yeast

AL Franklin, A Macfadden, JS Kieft, JR Hesselberth… - bioRxiv, 2020 - biorxiv.org
Structured RNA elements that protect RNA transcripts from 5’→3’ degradation are
becoming useful research tools. Here we show that exonuclease-resistant RNA structures (xrRNAs) …

Translation of Partially-decayed Messenger RNAs in Yeast

AL Franklin - 2019 - search.proquest.com
Flaviviruses are positive-strand single-stranded RNA viruses that are known to form pseudo-knot
RNA structures that halt the progression of 5'→ 3’exonuclease Xrn1. We show that …

Chemical development of CI-1008, an enantiomerically pure anticonvulsant

…, VS Hendrickson, LC Franklin… - … Process Research & …, 1997 - ACS Publications
Development of a manufacturing process for (S)-3-(aminomethyl)-5-methylhexanoic acid,
an anticonvulsant, is described. Initial preparation employed an Evans chiral alkylation on (4R,…

Comparative survival of patients with anal adenocarcinoma, squamous cell carcinoma of the anus, and rectal adenocarcinoma

RA Franklin, S Giri, P Valasareddy, LT Lands… - Clinical colorectal …, 2016 - Elsevier
… intestine extending from the anorectal ring to the anal verge, is complex, marked by the …
known to originate within the anal canal. Tumors originating within the anal canal comprise only …

[HTML][HTML] Factors influencing referrals for ultrasound-diagnosed complications during prenatal care in five low and middle income countries

HL Franklin, W Mirza, DL Swanson, JE Newman… - Reproductive …, 2018 - Springer
Background Ultrasound during antenatal care (ANC) is proposed as a strategy for increasing
hospital deliveries for complicated pregnancies and improving maternal, fetal, and …

Successful treatment of chronic anal fissure with diltiazem gel

R DasGupta, I Franklin, J Pitt, PM Dawson - Colorectal disease, 2002 - Wiley Online Library
Anal fissure is a common and painful condition that often affects … anal pressure [7] and
heals chronic anal fissures [8,9]. We present a prospective series of patients with chronic anal

[PDF][PDF] Evaluation of the effects of ethanol on monolayer and 3D models of human oral mucosa

K Moharamzadeh, KL Franklin, LE Smith… - … of Environmental & …, 2015 - researchgate.net
The aim of this study was to examine and compare the effects of different ethanol-containing
solutions on a 3D oral mucosal model (OMM) with those of fresh oral mucosal biopsies and …

[HTML][HTML] Including ultrasound scans in antenatal care in low-resource settings: Considering the complementarity of obstetric ultrasound screening and maternity …

DL Swanson, HL Franklin, JO Swanson… - Seminars in …, 2019 - Elsevier
Recent World Health Organization (WHO) antenatal care recommendations include an
ultrasound scan as a part of routine antenatal care. The First Look Study, referenced in the WHO …

[PDF][PDF] Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

…, Q Cai, CL Sears, JR Goldenring, JL Franklin… - Cell, 2021 - cell.com
Colorectal cancers (CRCs) arise from precursor polyps whose cellular origins, molecular
heterogeneity, and immunogenic potential may reveal diagnostic and therapeutic insights …

FRANKLIN RIET-CORREA1, MARIA C. MÉNDEZ1, ANA L. SCHILD1, JOAO A. OLIVEIRA1

H Tsunoda, MH Yu - … Research 1985: Selected Papers from the …, 1986 - books.google.com
Dental lesions in cattle were studied in 11 farms located within 1.2 to 9.6 km from a coal
combustion thermoelectric plant. Incisor teeth of some cattle showed evidence of chronic fluoride …