User profiles for Ana Marija Jaksic

Ana Marija Jakšić

EPFL
Verified email at epfl.ch
Cited by 371

[HTML][HTML] Genetic redundancy fuels polygenic adaptation in Drosophila

N Barghi, R Tobler, V Nolte, AM Jakšić, F Mallard… - PLoS …, 2019 - journals.plos.org
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …

The Interplay of Temperature and Genotype on Patterns of Alternative Splicing in Drosophila melanogaster

AM Jakšić, C Schlötterer - Genetics, 2016 - academic.oup.com
Alternative splicing is the highly regulated process of variation in the removal of introns from
premessenger-RNA transcripts. The consequences of alternative splicing on the phenotype …

Rapid sex-specific adaptation to high temperature in Drosophila

SK Hsu, AM Jakšić, V Nolte, M Lirakis, R Kofler… - Elife, 2020 - elifesciences.org
The pervasive occurrence of sexual dimorphism demonstrates different adaptive strategies
of males and females. While different reproductive strategies of the two sexes are well-…

Neuronal Function and Dopamine Signaling Evolve at High Temperature in Drosophila

AM Jakšić, J Karner, V Nolte, SK Hsu… - Molecular biology …, 2020 - academic.oup.com
Neuronal activity is temperature sensitive and affects behavioral traits important for
individual fitness, such as locomotion and courtship. Yet, we do not know enough about the …

Contesting the evidence for non-adaptive plasticity

F Mallard, AM Jakšić, C Schlötterer - Nature, 2018 - nature.com
Whether phenotypic plasticity generally facilitates or hampers adaptive evolution is a matter
of much debate. By comparing gene expression changes in guppy populations, Ghalambor …

Regulation of transposable elements: Interplay between TE‐encoded regulatory sequences and host‐specific trans‐acting factors in Drosophila melanogaster

AM Jakšić, R Kofler, C Schlötterer - Molecular Ecology, 2017 - Wiley Online Library
Transposable elements (TEs) are mobile genetic elements that can move around the genome,
and their expression is one precondition for this mobility. Because the insertion of TEs in …

[HTML][HTML] A 24 h age difference causes twice as much gene expression divergence as 100 generations of adaptation to a novel environment

SK Hsu, AM Jakšić, V Nolte, N Barghi, F Mallard… - Genes, 2019 - mdpi.com
Gene expression profiling is one of the most reliable high-throughput phenotyping methods,
allowing researchers to quantify the transcript abundance of expressed genes. Because …

Polygenic adaptation fuels genetic redundancy in Drosophila

N Barghi, R Tobler, V Nolte, AM Jaksic, F Mallard… - BioRxiv, 2018 - biorxiv.org
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic – ie result from selection on a large number of …

Evolution of phenotypic variance provides insights into the genetic basis of adaptation

WY Lai, V Nolte, AM Jakšić… - Genome Biology and …, 2024 - academic.oup.com
Most traits are polygenic, and the contributing loci can be identified by GWAS. The genetic
basis of adaptation is, however, difficult to characterize. Here, we propose to study the genetic …

Pre-and post-mating reproductive isolation evolve independently during rapid adaptation to high temperature

SK Hsu, WY Lai, J Novak, F Lehner, AM Jakšić… - bioRxiv, 2021 - biorxiv.org
Ambient temperature is one major ecological factor driving adaptation in natural populations,
but its impact on the emergence of new species is not yet clear. Here, we explored the …