User profiles for Ana P. Estrada-Florez

Ana Estrada-Florez

PhD Biomedical Science, University of Caldas
Verified email at ut.edu.co
Cited by 528

A polygenic risk score for breast cancer in US Latinas and Latin American women

…, AP Estrada-Flórez… - JNCI: Journal of the …, 2020 - academic.oup.com
Background More than 180 single nucleotide polymorphisms (SNPs) associated with breast
cancer susceptibility have been identified; these SNPs can be combined into polygenic risk …

Human epidermal growth factor receptor 2–positive breast cancer is associated with indigenous American ancestry in Latin American women

…, G Polanco-Echeverry, AP Estrada-Florez… - Cancer research, 2020 - AACR
The positive association between Indigenous American genetic ancestry and HER2 + breast
cancer suggests that the high incidence of HER2 + subtypes in Latinas might be due to …

[HTML][HTML] BRAF and TERT mutations in papillary thyroid cancer patients of Latino ancestry

AP Estrada-Flórez, ME Bohórquez… - Endocrine …, 2019 - ec.bioscientifica.com
Papillary thyroid cancer (PTC) is the second most commonly diagnosed malignancy in US
Latinas and in Colombian women. Studies in non-Latinos indicate that BRAF and TERT …

[HTML][HTML] Clinical features of Hispanic thyroid cancer cases and the role of known genetic variants on disease risk

AP Estrada-Florez, ME Bohórquez, R Sahasrabudhe… - Medicine, 2016 - journals.lww.com
Thyroid cancer (TC) is the second most common cancer among Hispanic women. Recent
genome-wide association (GWA) and candidate studies identified 6 single nucleotide …

Multiregional sequencing analysis reveals extensive genetic heterogeneity in gastric tumors from Latinos

TW Toal, AP Estrada-Florez… - Cancer research …, 2022 - AACR
Gastric cancer is a leading cause of cancer mortality and health disparities in Latinos. We
evaluated gastric intratumoral heterogeneity using multiregional sequencing of >700 cancer …

Associations between somatic mutations and clinical manifestations in South American Hispanic patients with papillary thyroid cancer

AP Estrada-Florez, ME Bohorquez, CS Duque… - Cancer Research, 2018 - AACR
Papillary thyroid cancer (PTC) is the second most commonly diagnosed tumor in US Hispanic
women, representing ~9% of all incident female cancer cases in this minority. In Colombia, …

[PDF][PDF] A polygenic risk score for breast cancer in US Latinas and Latin-American women

…, G Polanco-Echeverry, AP Estrada-Florez… - 2019 - researchgate.net
Background: Over 180 single nucleotide polymorphisms (SNPs) associated with breast
cancer susceptibility have been identified; these SNPs can be combined into polygenic risk …

Identification of predisposition and progression gastric cancer biomarkers in Latinos

AP Estrada-Florez, P Lott, T Toal, N Halmai, E Quino… - Cancer Research, 2022 - AACR
Gastric cancer (GC) disproportionally affects people of Latino ancestry and represent a leading
cause of incidence and mortality disparities in this minority populations. When compared …

Preclinical studies of chemotherapies and targeted therapies to address gastric cancer disparities

H Zhang, AP Estrada-Florez, P Lott, TW Toal… - Cancer Research, 2022 - AACR
Gastric cancer (GC) is one of the most common malignant tumors of the digestive system,
and its prognosis remains poor because most tumors were detected in late stages and the 5-…

[HTML][HTML] Haplotype analysis of the internationally distributed BRCA1 c.3331_3334delCAAG founder mutation reveals a common ancestral origin in Iberia

…, C Ramirez, A Criollo, A Estrada-Florez… - Breast cancer …, 2020 - Springer
Background The BRCA1 c.3331_3334delCAAG founder mutation has been reported in
hereditary breast and ovarian cancer families from multiple Hispanic groups. We aimed to …