The powerful world of antisense oligonucleotides: From bench to bedside

AM Quemener, L Bachelot, A Forestier… - Wiley …, 2020 - Wiley Online Library
Antisense oligonucleotides (ASOs) represent a new and highly promising class of drugs for
personalized medicine. In the last decade, major chemical developments and improvements …

CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance

…, M Aubry, D Leclerc, AM Quéméner… - EMBO Molecular …, 2021 - embopress.org
Most genetic alterations that drive melanoma development and resistance to targeted therapy
have been uncovered. In contrast, and despite their increasingly recognized contribution, …

[HTML][HTML] Small drugs, huge impact: the extraordinary impact of antisense oligonucleotides in research and drug development

AM Quemener, ML Centomo, SL Sax, R Panella - Molecules, 2022 - mdpi.com
Antisense oligonucleotides (ASOs) are an increasingly represented class of drugs. These
small sequences of nucleotides are designed to precisely target other oligonucleotides, …

Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19

AM Quemener, MD Galibert - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
The COVID‐19 crisis and the development of the first approved mRNA vaccine have highlighted
the power of RNA‐based therapeutic strategies for the development of new medicines. …

Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16

AM Quemener, L Bachelot, M Aubry… - Life Science …, 2022 - life-science-alliance.org
Uveal melanoma (UM), the most common primary intraocular tumor in adults, has been
extensively characterized by omics technologies during the last 5 yr. Despite the discovery of …

Gain-of-function CRISPR screens identify tumor-promoting genes conferring melanoma cell plasticity and therapy-resistance

…, L Bachelot, AM Quéméner, S Corre, M Aubry… - bioRxiv, 2020 - biorxiv.org
Most genetic alterations that drive melanoma development and resistance to targeted therapy
have been uncovered. In contrast, and despite their increasingly recognized contribution, …

Uveal Melanoma: a miR-16 disease?

AM Quéméner, L Bachelot, M Aubry, S Avner… - bioRxiv, 2021 - biorxiv.org
Uveal melanoma (UM), the most common primary intraocular tumor in adults, has been
extensively characterized by omics technologies during the last 5 years. Despite the discovery of …

[HTML][HTML] Direction colloque《 Surveillance》

…, PA Clément, PLM De Gouville, M Quéméner… - L. Laref, M. Laref (dir.) …, 2023 - hal.science
Programme 1re journée de colloque jeudi 6 avril 2023 8h30 9h00 Accueil des participants
OUVERTURE DU COLLOQUE (Allocutions et mots d’accueil) Mot d’introduction Nicolas …

Human Brain Tissue Identification Using Coherent Anti-Stokes Raman Scattering Spectroscopy and Diffuse Reflectance Spectroscopy for Deep Brain Stimulation …

…, M Takech, É Philippe, D DePaoli, L Cantin, M Parent… - 2023 - researchsquare.com
We assess the feasibility of using diffuse reflectance spectroscopy (DRS) and coherent anti-Stokes
Raman scattering spectroscopy (CARS) as optical tools for human brain tissue …

Human Neuronavigation Using Coherent Anti-Sokes Raman Scattering Spectroscopy and Diffuse Reflectance Spectroscopy for Deep Brain Stimulation Surgery

M Quémener, A Bédard, T Charland, D DePaoli… - Optics and the …, 2023 - opg.optica.org
Deep brain stimulation (DBS) surgery is performed on patients suffering Parkinson’s disease
for whom medication is no longer effective in relieving their symptoms. The outcomes of the …