Characterization of carbohydrate metabolism in in vivo-and in vitro-grown and matured mouse antral follicles

AC Herta, L von Mengden, N Akin… - Biology of …, 2022 - academic.oup.com
Establishing an ideal human follicle culture system for oncofertility patients relies mainly on
animal models since donor tissue is scarce and often of suboptimal quality. The in vitro …

Glucose metabolism characterization during mouse in vitro maturation identifies alterations in cumulus cells

N Akin, L von Mengden, AC Herta… - Biology of …, 2021 - academic.oup.com
In vitro maturation (IVM) is an assisted reproduction technique with reduced hormone-related
side-effects. Several attempts to implement IVM in routine practice have failed, primarily …

[HTML][HTML] Genome-wide assessment of DNA methylation in mouse oocytes reveals effects associated with in vitro growth, superovulation, and sexual maturity

…, E Ivanova, K Billooye, AC Herta… - Clinical …, 2019 - Springer
Background In vitro follicle culture (IFC), as applied in the mouse system, allows the growth
and maturation of a large number of immature preantral follicles to become mature and …

Effect of cumulin and super-GDF9 in standard and biphasic mouse IVM

N Akin, D Richani, X Liao, Y Zhao, AC Herta… - Journal of Assisted …, 2022 - Springer
Purpose In vitro maturation (IVM) is a technology that generates mature oocytes following
culture of immature cumulus-oocyte complexes (COC) in vitro. IVM is characterized by minimal …

Effects of lactate, super-GDF9, and low oxygen tension during bi-phasic in vitro maturation on the bioenergetic profiles of mouse cumulus–oocyte complex

N Akin, G Ates, L von Mengden, AC Herta… - Biology of …, 2023 - academic.oup.com
In vitro maturation (IVM) is an alternative assisted reproductive technology with reduced
hormone-related side effects and treatment burden compared to conventional IVF. Capacitation (…

Reversing complete mechanical transzonal projections disruption during mouse in vitro follicle culture with unaltered oocyte competence

AC Herta, N Akin, K Billooye… - Biology of …, 2021 - academic.oup.com
In vitro oocyte growth is widely studied as an alternative fertility preservation approach.
Several animal models are used to generate extensive information on this complex process …

[HTML][HTML] Genome-wide assessment of DNA methylation alterations induced by superovulation, sexual immaturity and in vitro follicle growth in mouse blastocysts

L Saucedo-Cuevas, E Ivanova, AC Herta, F Krueger… - Clinical …, 2023 - Springer
Background In their attempt to fulfill the wish of having children, women who suffer from
fertility issues often undergo assisted reproductive technologies such as ovarian stimulation, …

Glucose and redox metabolism in meiotically blocked in vitro grown mouse antral follicles

AC Herta, L von Mengden, N Akin, K Billooye… - Journal of Assisted …, 2023 - Springer
Purpose Glucose and redox metabolism characterization in mouse antral follicles with
meiotically blocked oocytes, after in vitro follicle culture (IFC) from the early secondary stage. …

[HTML][HTML] Correction to: Genome-wide assessment of DNA methylation in mouse oocytes reveals effects associated with in vitro growth, superovulation, and sexual …

…, E Ivanova, K Billooye, AC Herta… - Clinical …, 2020 - Springer
Anamaria-Cristina Herta … Maria Desemparats Saenz-de-Juano, Katy Billooye,
Anamaria-Cristina Herta, Johan Smitz & Ellen Anckaert … Anamaria-Cristina Herta

[HTML][HTML] In vitro culture of oocytes from early preantral-stage mouse follicles: repair of interconnectivity with cumulus and role of glucose metabolism

AC Herta - 2023 - researchportal.vub.be
An increasing proportion of young cancer survivors are using cryopreserved ovarian tissue (OTC)
if they confront infertility due to gonadotoxic cancer treatment. Nevertheless, OTC is …