Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …

While persistence of fear memories is essential for survival, a failure to inhibit fear in response
to harmless stimuli is a feature of anxiety disorders. Extinction training only temporarily …

This study investigates the effects of ethanol on neuronal and astroglial metabolism using 1
H‐[ 13 C]‐ NMR spectroscopy in conjunction with infusion of [1,6‐ 13 C 2 ]/[1‐ 13 C]glucose …

Major depressive disorder is the leading cause of disability and suicidality worldwide. Here,
we evaluated neural metabolic activity in prefrontal cortex (PFC) in C57BL6 mice …

RNA interference represents a novel therapeutic approach to modulate several
neurodegenerative disease-related genes. However, exogenous delivery of siRNA restricts their …

Chronic manganese (Mn) exposure in rodents, non-human primates and humans has been
linked to Parkinson’s disease like condition known as Manganism. Mn being a cofactor for …

Healthy aging is associated with a decline in cognitive function, and is a major risk factor for
many neurodegenerative diseases. Although, there are several evidence that brain …

Mononuclear and dinuclear Ru(II) complexes of 1,10-phenanthroline containing
aryldiazopentane-2,4-diones (L1H–L3H2) as co-ligands were prepared and characterised using IR, …

Background and Purpose The effects of nicotine on cerebral metabolism and its influence on
smoking behavior is poorly understood. An understanding of the chronic effects of nicotine …

Systemic delivery of nucleic acids to the central nervous system (CNS) is a major challenge
for the development of RNA interference-based therapeutics due to lack of stability, target …