… Anatol Fritsch, Tobias Kiessling, Kenechukwu David Nnetu, Franziska Wetzel, Mareike
Zink and Josef A. Käs: Anatol Fritsch, Tobias Kiessling, Kenechuku David Nnetu, Franziska …

Cell motility and cell shape adaptations are crucial during wound healing, inflammation, and
malignant progression. These processes require the remodeling of the keratin cytoskeleton …

Liquid–liquid phase separation (LLPS) of proteins containing intrinsically disordered
regions (IDRs) has been proposed as a mechanism underlying the formation of membrane-less …

Membraneless compartments, also known as condensates, provide chemically distinct
environments and thus spatially organize the cell. A well-studied example of condensates is P …

Tissue, cell, and nucleus morphology change during tumor progression. In 2D confluent cell
cultures, different tissue states, such as fluid (unjammed) and solid (jammed), are correlated …

Cells sense elevated temperatures and mount an adaptive heat shock response that involves
changes in gene expression, but the underlying mechanisms, particularly on the level of …

It has long been proposed that phase-separated compartments can provide a basis for the
formation of cellular precursors in prebiotic environments. However, we know very little about …

Recent advances in cell biology enable precise molecular perturbations. The spatiotemporal
organization of cells and organisms, however, also depends on physical processes such …

The optical cell rotator (OCR) is a modified dual-beam laser trap for the holding and
controlled rotation of suspended dielectric microparticles, such as cells. In contrast to optical …

We analyze the mechanical properties of three epithelial/mesenchymal cell lines (MCF-10A,
MDA-MB-231, MDA-MB-436) that exhibit a shift in E-, N-and P-cadherin levels characteristic …