User profiles for Anders Jacobsen
Anders Jacobsen SkanderupGenome Institute of Singapore Verified email at gis.a-star.edu.sg Cited by 97784 |
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
The cBioPortal for Cancer Genomics ( http://cbioportal.org ) provides a Web resource for
exploring, visualizing, and analyzing multidimensional cancer genomics data. The portal …
exploring, visualizing, and analyzing multidimensional cancer genomics data. The portal …
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
The cBio Cancer Genomics Portal ( http://cbioportal.org ) is an open-access resource for
interactive exploration of multidimensional cancer genomics data sets, currently providing …
interactive exploration of multidimensional cancer genomics data sets, currently providing …
[HTML][HTML] The somatic genomic landscape of glioblastoma
We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …
[HTML][HTML] Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
LB Frankel, NR Christoffersen, A Jacobsen… - Journal of Biological …, 2008 - ASBMB
MicroRNAs are emerging as important regulators of cancer-related processes. The miR-21
microRNA is overexpressed in a wide variety of cancers and has been causally linked to …
microRNA is overexpressed in a wide variety of cancers and has been causally linked to …
[PDF][PDF] Genomic classification of cutaneous melanoma
We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …
[PDF][PDF] Integrated genomic characterization of papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
Genome-wide analysis of noncoding regulatory mutations in cancer
Cancer primarily develops because of somatic alterations in the genome. Advances in
sequencing have enabled large-scale sequencing studies across many tumor types, emphasizing …
sequencing have enabled large-scale sequencing studies across many tumor types, emphasizing …
[HTML][HTML] miR-449 inhibits cell proliferation and is down-regulated in gastric cancer
T Bou Kheir, E Futoma-Kazmierczak, A Jacobsen… - Molecular cancer, 2011 - Springer
Background Gastric cancer is the fourth most common cancer in the world and the second
most prevalent cause of cancer related death. The development of gastric cancer is mainly …
most prevalent cause of cancer related death. The development of gastric cancer is mainly …
An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma
…, H Furberg, EC Zabor, A Jacobsen… - Journal of the …, 2013 - academic.oup.com
Background Obesity increases risk for clear-cell renal cell carcinoma (ccRCC), yet obese
patients appear to experience longer survival than nonobese patients. We examined body …
patients appear to experience longer survival than nonobese patients. We examined body …
[HTML][HTML] Analysis of microRNA-target interactions across diverse cancer types
A Jacobsen, J Silber, G Harinath, JT Huse… - Nature structural & …, 2013 - nature.com
Little is known about the extent to which individual microRNAs (miRNAs) regulate common
processes of tumor biology across diverse cancer types. Using molecular profiles of >3,000 …
processes of tumor biology across diverse cancer types. Using molecular profiles of >3,000 …