User profiles for André Fisahn
André FisahnKarolinska Institute Verified email at ki.se Cited by 6067 |
Interneurons unbound
Local-circuit, γ-aminobutyric acid-releasing inhibitory interneurons of the hippocampus and
cortex have traditionally been considered as the regulators of principal neuron activity — the …
cortex have traditionally been considered as the regulators of principal neuron activity — the …
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
Alzheimer's disease is an increasingly prevalent neurodegenerative disorder whose
pathogenesis has been associated with aggregation of the amyloid-β peptide (Aβ42). Recent …
pathogenesis has been associated with aggregation of the amyloid-β peptide (Aβ42). Recent …
Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro
Acetylcholine is vital for cognitive functions of the brain. Although its actions in the individual
cell are known in some detail 1 , its effects at the network level are poorly understood 2 . The …
cell are known in some detail 1 , its effects at the network level are poorly understood 2 . The …
A model of gamma‐frequency network oscillations induced in the rat CA3 region by carbachol in vitro
Carbachol (> 20 μm) and kainate (100 nm) induce, in the in vitro CA3 region, synchronized
neuronal population oscillations at ≈ 40 Hz having distinctive features: (i) the oscillations …
neuronal population oscillations at ≈ 40 Hz having distinctive features: (i) the oscillations …
Distinct roles for the kainate receptor subunits GluR5 and GluR6 in kainate-induced hippocampal gamma oscillations
Kainate receptors (KARs) play an important role in synaptic physiology, plasticity, and
pathological phenomena such as epilepsy. However, the physiological implications for neuronal …
pathological phenomena such as epilepsy. However, the physiological implications for neuronal …
[PDF][PDF] Muscarinic induction of hippocampal gamma oscillations requires coupling of the M1 receptor to two mixed cation currents
Oscillatory network activity at γ frequencies is assumed to be of major importance in cortical
information processing. Whereas the synaptic mechanisms of γ oscillations have been …
information processing. Whereas the synaptic mechanisms of γ oscillations have been …
Neuregulin-1 modulates hippocampal gamma oscillations: implications for schizophrenia
A Fisahn, J Neddens, L Yan, A Buonanno - Cerebral cortex, 2009 - academic.oup.com
Alterations in gamma-frequency oscillations are implicated in psychiatric disorders, and
polymorphisms in NRG-1 and ERBB4, genes encoding Neuregulin-1 (NRG-1) and one of its …
polymorphisms in NRG-1 and ERBB4, genes encoding Neuregulin-1 (NRG-1) and one of its …
Chemically defined, albumin-free human cardiomyocyte generation
To the Editor: Human pluripotent stem cell (hPSC)-derived cardiomyocytes are important tools
for cardiovascular research and have substantial therapeutic potential. Several efficient di …
for cardiovascular research and have substantial therapeutic potential. Several efficient di …
Cholinergic activation and tonic excitation induce persistent gamma oscillations in mouse somatosensory cortex in vitro
EH Buhl, G Tamás, A Fisahn - The Journal of physiology, 1998 - Wiley Online Library
1 Concomitant application of the cholinergic agonist carbachol and nanomolar doses of
kainate can elicit persistent gamma frequency oscillations in all layers of the mouse …
kainate can elicit persistent gamma frequency oscillations in all layers of the mouse …
Amyloid-β-induced action potential desynchronization and degradation of hippocampal gamma oscillations is prevented by interference with peptide conformation …
…, J Johansson, B Winblad, A Fisahn - Journal of …, 2014 - Soc Neuroscience
The amyloid-β hypothesis of Alzheimer's Disease (AD) focuses on accumulation of amyloid-β
peptide (Aβ) as the main culprit for the myriad physiological changes seen during …
peptide (Aβ) as the main culprit for the myriad physiological changes seen during …