User profiles for André Fisahn

André Fisahn

Karolinska Institute
Verified email at ki.se
Cited by 6067

Interneurons unbound

CJ McBain, A Fisahn - Nature Reviews Neuroscience, 2001 - nature.com
Local-circuit, γ-aminobutyric acid-releasing inhibitory interneurons of the hippocampus and
cortex have traditionally been considered as the regulators of principal neuron activity — the …

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

…, J Johansson, CM Dobson, A Fisahn… - Nature structural & …, 2015 - nature.com
Alzheimer's disease is an increasingly prevalent neurodegenerative disorder whose
pathogenesis has been associated with aggregation of the amyloid-β peptide (Aβ42). Recent …

Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro

A Fisahn, FG Pike, EH Buhl, O Paulsen - Nature, 1998 - nature.com
Acetylcholine is vital for cognitive functions of the brain. Although its actions in the individual
cell are known in some detail 1 , its effects at the network level are poorly understood 2 . The …

A model of gamma‐frequency network oscillations induced in the rat CA3 region by carbachol in vitro

RD Traub, A Bibbig, A Fisahn… - European Journal of …, 2000 - Wiley Online Library
Carbachol (> 20 μm) and kainate (100 nm) induce, in the in vitro CA3 region, synchronized
neuronal population oscillations at ≈ 40 Hz having distinctive features: (i) the oscillations …

Distinct roles for the kainate receptor subunits GluR5 and GluR6 in kainate-induced hippocampal gamma oscillations

A Fisahn, A Contractor, RD Traub, EH Buhl… - Journal of …, 2004 - Soc Neuroscience
Kainate receptors (KARs) play an important role in synaptic physiology, plasticity, and
pathological phenomena such as epilepsy. However, the physiological implications for neuronal …

[PDF][PDF] Muscarinic induction of hippocampal gamma oscillations requires coupling of the M1 receptor to two mixed cation currents

A Fisahn, M Yamada, A Duttaroy, JW Gan, CX Deng… - Neuron, 2002 - cell.com
Oscillatory network activity at γ frequencies is assumed to be of major importance in cortical
information processing. Whereas the synaptic mechanisms of γ oscillations have been …

Neuregulin-1 modulates hippocampal gamma oscillations: implications for schizophrenia

A Fisahn, J Neddens, L Yan, A Buonanno - Cerebral cortex, 2009 - academic.oup.com
Alterations in gamma-frequency oscillations are implicated in psychiatric disorders, and
polymorphisms in NRG-1 and ERBB4, genes encoding Neuregulin-1 (NRG-1) and one of its …

Chemically defined, albumin-free human cardiomyocyte generation

X Lian, X Bao, M Zilberter, M Westman, A Fisahn… - Nature …, 2015 - nature.com
To the Editor: Human pluripotent stem cell (hPSC)-derived cardiomyocytes are important tools
for cardiovascular research and have substantial therapeutic potential. Several efficient di …

Cholinergic activation and tonic excitation induce persistent gamma oscillations in mouse somatosensory cortex in vitro

EH Buhl, G Tamás, A Fisahn - The Journal of physiology, 1998 - Wiley Online Library
1 Concomitant application of the cholinergic agonist carbachol and nanomolar doses of
kainate can elicit persistent gamma frequency oscillations in all layers of the mouse …

Amyloid-β-induced action potential desynchronization and degradation of hippocampal gamma oscillations is prevented by interference with peptide conformation …

…, J Johansson, B Winblad, A Fisahn - Journal of …, 2014 - Soc Neuroscience
The amyloid-β hypothesis of Alzheimer's Disease (AD) focuses on accumulation of amyloid-β
peptide (Aβ) as the main culprit for the myriad physiological changes seen during …