The immune system undergoes major changes with age that result in altered immune
populations, persistent inflammation, and a reduced ability to mount effective immune responses …

The Sirtuin family of NAD + -dependent enzymes plays an important role in maintaining genome
stability upon stress. Several mammalian Sirtuins have been linked directly or indirectly …

Death receptor ligand TRAIL is a promising cancer therapy due to its ability to selectively
trigger extrinsic apoptosis in cancer cells. However, TRAIL–based therapies in humans have …

Autophagy is a highly conserved intracellular process that preserves cellular homeostasis
by mediating the lysosomal degradation of virtually any component of the cytoplasm. …

Death receptor ligand TRAIL is a promising cancer therapy due to its ability to selectively
trigger extrinsic apoptosis in cancer cells. However, TRAIL–based therapies in humans have …

El adenocarcinoma pancreático es uno de los tumores sólidos con peor pronóstico. Su
creciente incidencia la proyecta a constituir la segunda causa de muertes relacionadas con el …

Antecedentes La Sociedad Española de Neumología y Cirugía Torácica (SEPAR) promueve,
a través del Área de Cirugía Torácica, la elaboración del presente documento con el …

… 10 , Pablo Gámez García … 15 , Juan José Rivas de Andrés …

… Henar Borrego Pintado h , Carlos Disdier Vicente i , Javier Flandes Aldeyturriaga j , Pablo
Gámez García k , Pilar Garrido López l , Pablo León Atance m , José Miguel Izquierdo Elena n …

Background. Extended cervical mediastinoscopy (ECM) is a technique in the staging of
bronchogenic carcinoma described first by Ginsberg in 1984. To update our experience we have …