An increasingly powerful approach for studying brain circuits relies on targeting genetically
encoded sensors and effectors to specific cell types. However, current approaches for this …

The local field potential (LFP) is increasingly used to measure the combined activity of
neurons within a region of tissue. Yet, available estimates of the size of this region are highly …

The visual cortex represents stimuli through the activity of neuronal populations. We measured
the evolution of this activity in space and time by imaging voltage-sensitive dyes in cat …

The response of neurons in sensory cortex to repeated stimulus presentations is highly variable.
To investigate the nature of this variability, we compared the spike activity of neurons in …

Sensory systems exhibit mechanisms of neural adaptation, which adjust neuronal activity
on the basis of recent stimulus history. In primary visual cortex (V1) in particular, adaptation …

Genetically encoded voltage indicators (GEVIs) promise to reveal the membrane potential
of genetically targeted neuronal populations through noninvasive, chronic imaging of large …

The organization of primary visual cortex (V1) into functional maps makes individual cells
operate in a variety of contexts. For instance, some neurons lie in regions of fairly …

Hemodynamic responses in mice and other species are typically measured under anesthesia.
However, anesthesia could influence their relationship to neural activity. To investigate …

In recent years, the number of studies on decision-making in mice has increased dramatically.
Many of these studies focus on the posterior parietal cortex (PPC), an area that has been …

Cortical circuits encode sensory stimuli through the firing of neuronal ensembles, and also
produce spontaneous population patterns in the absence of sensory drive. This population …