User profiles for Andrea Cox

Andrea Cox

Professor of Medicine, Johns Hopkins University
Verified email at jhmi.edu
Cited by 14006

Characterization of peptides bound to the class I MHC molecule HLA-A2. 1 by mass spectrometry

…, K Sakaguchi, H Michel, N Sevilir, AL Cox… - Science, 1992 - science.org
Antigens recognized by T cells are expressed as peptides bound to major histocompatibility
complex (MHC) molecules. Microcapillary high-performance liquid chromatography-…

Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines

AL Cox, J Skipper, Y Chen, RA Henderson, TL Darrow… - Science, 1994 - science.org
Of several thousand peptides presented by the major histocompatibility molecule HLA-A2.1,
at least nine are recognized by melanoma-specific cytotoxic T lymphocytes (CTLs). Tandem …

Peptides Presented to the Immune System by the Murine Class II Major Histocompatibility Complex Molecule IAd

…, H Michel, TA Dickinson, J Shabanowitz, AL Cox… - Science, 1992 - science.org
Between 650 and 2000 different peptides are associated with the major histocompatibility
complex class II molecule IA d . Sequences for nine of these were obtained by a combination …

[PDF][PDF] The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection

…, MD Morris, B Hajarizadeh, J Amin, AL Cox… - …, 2014 - Wiley Online Library
Although 20%‐40% of persons with acute hepatitis C virus (HCV) infection demonstrate
spontaneous clearance, the time course and factors associated with clearance remain poorly …

Protection against persistence of hepatitis C

SH Mehta, A Cox, DR Hoover, XH Wang, Q Mao, S Ray… - The Lancet, 2002 - thelancet.com
Background Neither previous hepatitis C virus (HCV) infection nor vaccination with HCV-derived
antigens protects against reinfection. However, HCV infection and vaccination in …

Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection

…, G Urban, L Liu, SC Ray, DL Thomas, AL Cox - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: We followed patients with ongoing hepatitis C virus (HCV) exposure
following control of an initial HCV infection to determine whether primary control conferred …

A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety …

…, M Giedlin, JL Louis, EA Sugar, A Pons, AL Cox… - Clinical cancer …, 2012 - AACR
Purpose: Listeria monocytogenes (Lm)-based vaccines stimulate both innate and adaptive
immunity. ANZ-100 is a live-attenuated Lm strain (Lm ΔactA/ΔinlB). Uptake by phagocytes in …

Cellular immune selection with hepatitis C virus persistence in humans

AL Cox, T Mosbruger, Q Mao, Z Liu, XH Wang… - The Journal of …, 2005 - rupress.org
Hepatitis C virus (HCV) infection frequently persists despite substantial virus-specific cellular
immune responses. To determine if immunologically driven sequence variation occurs with …

Human immunodeficiency virus-related microbial translocation and progression of hepatitis C

…, A Mehta, R Long, GD Kirk, SH Mehta, AL Cox… - Gastroenterology, 2008 - Elsevier
Background & Aims: Human immunodeficiency virus (HIV)-1 infection has been associated
with enhanced microbial translocation, and microbial translocation is a mechanism through …

Prospective evaluation of community-acquired acute-phase hepatitis C virus infection

AL Cox, DM Netski, T Mosbruger… - Clinical infectious …, 2005 - academic.oup.com
Background . More than two-thirds of hepatitis C virus (HCV) infections in Western countries
are caused by injection drug use, but prospective clinical data regarding the most common …