[HTML][HTML] SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory …
ME Francis, U Goncin, A Kroeker, C Swan… - PLoS …, 2021 - journals.plos.org
COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …
Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection
Ebola outbreaks occur on a frequent basis, with the 2014-2015 outbreak in West Africa being
the largest one ever recorded. This outbreak has resulted in over 11,000 deaths in four …
the largest one ever recorded. This outbreak has resulted in over 11,000 deaths in four …
[PDF][PDF] Antibody treatment of Ebola and Sudan virus infection via a uniquely exposed epitope within the glycoprotein receptor-binding site
…, HL Turner, J Pallesen, CD Murin, S He, A Kroeker… - Cell reports, 2016 - cell.com
Previous efforts to identify cross-neutralizing antibodies to the receptor-binding site (RBS) of
ebolavirus glycoproteins have been unsuccessful, largely because the RBS is occluded on …
ebolavirus glycoproteins have been unsuccessful, largely because the RBS is occluded on …
Two-mAb cocktail protects macaques against the Makona variant of Ebola virus
…, H Wei, L Luo, L Fernando, A Kroeker… - Science translational …, 2016 - science.org
The 2014–2015 Ebola virus (EBOV) outbreak in West Africa highlighted the urgent need for
specific therapeutic interventions for infected patients. The human-mouse chimeric …
specific therapeutic interventions for infected patients. The human-mouse chimeric …
Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1
Subcellular trafficking within host cells plays a critical role in viral life cycles, including
influenza A virus (IAV). Thus targeting relevant subcellular compartments holds promise for …
influenza A virus (IAV). Thus targeting relevant subcellular compartments holds promise for …
Response of primary human airway epithelial cells to influenza infection: a quantitative proteomic study
AL Kroeker, P Ezzati, AJ Halayko… - Journal of Proteome …, 2012 - ACS Publications
Influenza A virus exerts a large health burden during both yearly epidemics and global
pandemics. However, designing effective vaccine and treatment options has proven difficult since …
pandemics. However, designing effective vaccine and treatment options has proven difficult since …
Ferrets infected with Bundibugyo virus or Ebola virus recapitulate important aspects of human filovirus disease
R Kozak, S He, A Kroeker, MA de La Vega… - Journal of …, 2016 - Am Soc Microbiol
Bundibugyo virus (BDBV) is the etiological agent of a severe hemorrhagic fever in humans
with a case-fatality rate ranging from 25 to 36%. Despite having been known to the scientific …
with a case-fatality rate ranging from 25 to 36%. Despite having been known to the scientific …
The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle
…, G Dueck, S Ghavami, A Kroeker… - American journal of …, 2011 - atsjournals.org
Smooth muscle cells promote fibroproliferative airway remodeling in asthma, and transforming
growth factor β1 (TGFβ1) is a key inductive signal. Statins are widely used to treat …
growth factor β1 (TGFβ1) is a key inductive signal. Statins are widely used to treat …
Data quality of electronic medical records in Manitoba: do problem lists accurately reflect chronic disease billing diagnoses?
A Singer, S Yakubovich, AL Kroeker… - Journal of the …, 2016 - academic.oup.com
Objective To determine problem list completeness related to chronic diseases in electronic
medical records (EMRs) and explore clinic and physician factors influencing completeness. …
medical records (EMRs) and explore clinic and physician factors influencing completeness. …
[HTML][HTML] Potent neutralizing monoclonal antibodies against Ebola virus infection
Ebola virus infections cause a deadly hemorrhagic disease for which no vaccines or
therapeutics has received regulatory approval. Here we show isolation of three (Q206, Q314 and …
therapeutics has received regulatory approval. Here we show isolation of three (Q206, Q314 and …