User profiles for Andrea Lauria

Andrea Lauria

University of Turin, Italy
Verified email at unito.it
Cited by 128

Metabolic control of DNA methylation in naive pluripotent cells

…, V Perrera, M Audano, S Rapelli, A Lauria… - Nature …, 2021 - nature.com
Naive epiblast and embryonic stem cells (ESCs) give rise to all cells of adults. Such developmental
plasticity is associated with genome hypomethylation. Here, we show that LIF–Stat3 …

[HTML][HTML] DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells

A Lauria, G Meng, V Proserpio, S Rapelli… - Nature …, 2023 - nature.com
The correct establishment of DNA methylation patterns during mouse early development is
essential for cell fate specification. However, the molecular targets as well as the …

[HTML][HTML] Tissue memory relies on stem cell priming in distal undamaged areas

…, M Watanabe, V Proserpio, G Piacenti, A Lauria… - Nature Cell …, 2023 - nature.com
Epithelial cells that participated in wound repair elicit a more efficient response to future
injuries, which is believed to be locally restricted. Here we show that cell adaptation resulting …

Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia

…, M Mezzanotte, C Pezzini, LB Bindels, A Lauria… - EMBO …, 2022 - embopress.org
Cachexia is a wasting syndrome characterized by devastating skeletal muscle atrophy that
dramatically increases mortality in various diseases, most notably in cancer patients with a …

Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles

A Lauria, S Peirone, MD Giudice, F Priante… - Nucleic acids …, 2020 - academic.oup.com
Heterogeneity is a fundamental feature of complex phenotypes. So far, genomic screenings
have profiled thousands of samples providing insights into the transcriptome of the cell. …

The acetyltransferase p300 is recruited in trans to multiple enhancer sites by lncSmad7

M Maldotti, A Lauria, F Anselmi, I Molineris… - Nucleic Acids …, 2022 - academic.oup.com
The histone acetyltransferase p300 (also known as KAT3B) is a general transcriptional
coactivator that introduces the H3K27ac mark on enhancers triggering their activation and gene …

Lifelong tissue memory relies on spatially organised dedicated progenitors located distally from the injury

…, M Watanabe, V Proserpio, G Piacenti, A Lauria… - bioRxiv, 2023 - biorxiv.org
It is believed epithelial cells that have participated in a wound repair elicit a more efficient but
locally restricted response to future injuries. However here we show that the cell adaptation …

Hair follicle stem cell progeny heal blisters while pausing skin development

…, H Nakamura, H Kosumi, Y Wang, Y Mai, A Lauria… - EMBO …, 2021 - embopress.org
Injury in adult tissue generally reactivates developmental programs to foster regeneration,
but it is not known whether this paradigm applies to growing tissue. Here, by employing …

[HTML][HTML] Expression and Function of C1orf132 Long-Noncoding RNA in Breast Cancer Cell Lines and Tissues

…, S Rahmani, N Nafissi, SJ Mowla, A Lauria… - International journal of …, 2021 - mdpi.com
miR-29b2 and miR-29c play a suppressive role in breast cancer progression. C1orf132 (also
named MIR29B2CHG) is the host gene for generating both microRNAs. However, the …

[HTML][HTML] Genome-Wide analysis of Smad7-mediated transcription in mouse embryonic stem cells

G Meng, A Lauria, M Maldotti, F Anselmi… - International Journal of …, 2021 - mdpi.com
Smad7 has been identified as a negative regulator of the transforming growth factor TGF-β
pathway by direct interaction with the TGF-β type I receptor (TβR-I). Although Smad7 has also …