User profiles for Andrea Low Hsiu Ling

Andrea Hsiu Ling Low

Singapore General Hospital
Verified email at sgh.com.sg
Cited by 633

IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts

…, S Schafer, B Reversade, S Albani, ALH Ling… - …, 2021 - academic.oup.com
Objectives Interleukin 11 (IL11) is highly upregulated in skin and lung fibroblasts from patients
with systemic sclerosis (SSc). Here we tested whether IL11 is mechanistically linked with …

B-cell targeted therapy with rituximab for thyroid eye disease: closer to the clinic

S Shen, A Chan, PP Sfikakis, ALH Ling… - Survey of …, 2013 - Elsevier
The management of thyroid eye disease (TED) remains a therapeutic challenge. The
current established therapies are unsatisfactory in one-third of the patients and have many …

Advances in biological and targeted therapies for systemic sclerosis

E Mulcaire-Jones, AHL Low, R Domsic… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Systemic sclerosis (SSc) is a severe, and often life-threatening, autoimmune
disease, which causes inflammation and fibrosis of the skin and internal organs. There are …

The microbiome and systemic sclerosis: A review of current evidence

TC Tan, M Noviani, YY Leung, AHL Low - Best Practice & Research …, 2021 - Elsevier
… Tze Chin Tan a b , Maria Noviani a b , Ying Ying Leung a b , Andrea Hsiu Ling Low a b …
with less severe dysbiosis, possibly associated with the lower prevalence of ILD in the OUH-SSc …

Disease characteristics of the Singapore systemic sclerosis cohort

ALH Ling, TG Gee, LW Giap… - Proceedings of …, 2013 - journals.sagepub.com
Introduction: Systemic sclerosis (SSc) has one of the worst prognoses among autoimmune
diseases. Multi-ethnic Western cohorts have shown ethnic differences in disease …

Recommendations for COVID‐19 vaccination in people with rheumatic disease: developed by the Singapore chapter of rheumatologists

…, A Lateef, TH Lee, KH Leong, AHL Low… - International Journal …, 2021 - Wiley Online Library
Aim People with rheumatic diseases (PRD) remain vulnerable in the era of the COVID‐19
pandemic. We formulated recommendations to meet the urgent need for a consensus for …

[HTML][HTML] A double-blind randomized placebo-controlled trial of probiotics in systemic sclerosis associated gastrointestinal disease

AHL Low, GG Teng, S Pettersson… - Seminars in arthritis and …, 2019 - Elsevier
Objective Assess whether treatment with probiotics improve gastrointestinal symptoms in
patients with systemic sclerosis (SSc). Methods In this double-blind randomized placebo-…

[HTML][HTML] Comparative analysis of single-cell RNA sequencing methods with and without sample multiplexing

…, AM Lajam, S Albani, AHL Low… - International Journal of …, 2024 - mdpi.com
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful technique for
investigating biological heterogeneity at the single-cell level in human systems and model …

Systemic sclerosis in Asians: are there racial differences?

SA Ng, AHL Low - Journal of Scleroderma and Related …, 2022 - journals.sagepub.com
Systemic sclerosis is a multisystemic autoimmune disease characterized by vasculopathy
and fibrosis. Racial factors exert a significant influence on the epidemiology, clinical …

Interval between symptom onset and diagnosis among patients with autoimmune rheumatic diseases in a multi‐ethnic Asian population

L Xiang, AHL Low, YY Leung, W Fong… - … journal of rheumatic …, 2021 - Wiley Online Library
Aim The interval between symptom onset and diagnosis (pre‐diagnosis interval) can at
times be longer than is ideal in patients with autoimmune rheumatic diseases (ARDs). In this …