User profiles for Andrea Martinez Aguirre

andrea aguirre

Ingénieur d'études, Brain Institute
Verified email at icm-institute.org
Cited by 174

[HTML][HTML] Bile acid-independent protection against Clostridioides difficile infection

AM Aguirre, N Yalcinkaya, Q Wu, A Swennes… - PLoS …, 2021 - journals.plos.org
Clostridioides difficile infections occur upon ecological / metabolic disruptions to the normal
colonic microbiota, commonly due to broad-spectrum antibiotic use. Metabolism of bile acids …

Gut associated metabolites and their roles in Clostridioides difficile pathogenesis

AM Aguirre, JA Sorg - Gut Microbes, 2022 - Taylor & Francis
The nosocomial pathogen Clostridioides difficile is a burden to the healthcare system. Gut
microbiome disruption, most commonly by broad-spectrum antibiotic treatment, is well …

[HTML][HTML] Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation

AM Aguirre, AO Adegbite, JA Sorg - npj Biofilms and Microbiomes, 2022 - nature.com
The Clostridioides difficile pathogen is responsible for nosocomial infections. Germination is
an essential step for the establishment of C. difficile infection (CDI) because toxins that are …

[HTML][HTML] A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile

E Marini, C Olivença, S Ramalhete, AM Aguirre… - Plos …, 2023 - journals.plos.org
A genomic signature for endosporulation includes a gene coding for a protease, YabG, which
in the model organism Bacillus subtilis is involved in assembly of the spore coat. We show …

The Selenophosphate Synthetase Gene, selD, Is Important for Clostridioides difficile Physiology

KN McAllister, A Martinez Aguirre… - Journal of Bacteriology, 2021 - Am Soc Microbiol
The endospore-forming pathogen Clostridioides difficile is the leading cause of antibiotic-associated
diarrhea and is a significant burden on the community and health care. C. difficile , …

Protease-stable DARPins as promising oral therapeutics

…, Y Zeng, V Chonira, AM Aguirre… - Protein Engineering …, 2021 - academic.oup.com
Clostridioides difficile is an enteric bacterium whose exotoxins, TcdA and TcdB, inactivate
small GTPases within the host cells, leading to bloody diarrhea. In prior work, our group …

The selenophosphate synthetase, selD, is important for Clostridioides difficile physiology

KN McAllister, AM Aguirre, JA Sorg - bioRxiv, 2021 - biorxiv.org
The endospore-forming pathogen, Clostridioides difficile, is the leading cause of antibiotic-associated
diarrhea and is a significant burden on the community and healthcare. C. difficile, …

Identifying the differences in survivorship and growth in offspring of large and small females in the pipefish species Syngnathus scovelli

A Martinez Aguirre - 2014 - oaktrust.library.tamu.edu
While maternal investment in many fish species is well studied, the effect of maternal
investment on offspring quality in the sex-role-reversed pipefish Syngnathus scovelli has not yet …

[PDF][PDF] IDENTIFYING THE DIFFERENCES IN SURVIVORSHIP AND GROWTH OF OFFSPRING OF LARGE AND SMALL FEMALES IN THE PIPEFISH SPECIES …

AM AGUIRRE - 2015 - core.ac.uk
While maternal investment in many fish species is well studied, the effect of maternal
investment on offspring quality in the sex-role-reversed pipefish Syngnathus scovelli has not yet …

Factors that Affect Clostridioides Difficile Infections Using In Vivo and In Vitro Approaches

A Martinez Aguirre - 2022 - oaktrust.library.tamu.edu
C. difficile a Gram-positive, spore-forming, pathogenic bacterium, is the leading cause of
nosocomial-associated diarrhea in the United States. C. difficile is characterized as an urgent …