Clustered attacks of epileptic episodes originating from the frontal lobe during sleep are the
main symptoms of autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE, MIM …

The timing of daily circadian behavior can be highly variable among different individuals, and
twin studies have suggested that about half of this variability is environmentally controlled. …

A platform for highly parallel direct sequencing of native RNA strands was recently described
by Oxford Nanopore Technologies, but despite initial efforts it remains crucial to further …

Molecular diversity of surface receptors has been hypothesized to provide a mechanism for
selective synaptic connectivity. Neurexins are highly diversified receptors that drive the …

We describe a pedigree in which eight individuals presented with a non-progressive disorder
with onset between the ages of 12 and 50 years. It was characterized by predominantly …

Armillaria species are both devastating forest pathogens and some of the largest terrestrial
organisms on Earth. They forage for hosts and achieve immense colony sizes via …

The mineralocorticoid hormone aldosterone controls sodium reabsorption and BP largely
by regulating the cell-surface expression and function of the epithelial sodium channel (ENaC) …

Community analyses of arbuscular mycorrhizal fungi ( AMF ) using ribosomal small subunit
( SSU ) or internal transcribed spacer ( ITS ) DNA sequences often suffer from low resolution …

Next-generation sequencing (NGS) technologies enable new insights into the diversity of
virus populations within their hosts. Diversity estimation is currently restricted to single-…

Type 1 diabetes is caused by autoimmune-mediated β cell destruction leading to insulin
deficiency. The histone deacetylase SIRT1 plays an essential role in modulating several age-…