OBJECTIVE: Alcohol dependence may be associated with dysfunction of mesolimbic circuitry,
such that anticipation of nonalcoholic reward fails to activate the ventral striatum, while …

Patients suffering from addiction persist in consuming substances of abuse, despite negative
consequences or absence of positive consequences. One potential explanation is that …

During rest, brain activity is synchronized between different regions widely distributed throughout
the brain, forming functional networks. However, the molecular mechanisms supporting …

Context Indicated prevention is currently regarded as the most promising strategy to attenuate,
delay, or even avert psychosis. Existing criteria need improvement in terms of specificity …

Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …

Context In alcohol-dependent patients, brain atrophy and functional brain activation elicited
by alcohol-associated stimuli may predict relapse. However, to date, the interaction between …

OBJECTIVE: In abstinent alcoholic patients, a low availability of dopamine D 2/3 receptors
in the ventral striatum and adjacent putamen was associated with a high level of craving for …

Objective: Amygdala volume has been associated with drug craving in cocaine addicts, and
amygdala volume reduction is observed in some alcohol-dependent subjects. This study …

Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

According to the World Health Organization (WHO), mental health is “a state of well-being in
which the individual realizes his or her own abilities, can cope with the normal stresses of life…