Sensitive interferometric detection of ultrasound for minimally invasive clinical imaging applications

…, S Kellnberger, D Bozhko, A Chekkoury… - Laser & Photonics …, 2014 - Wiley Online Library
Miniaturized optical detectors of ultrasound represent a promising alternative to piezoelectric
technology and may enable new minimally invasive clinical applications, particularly in the …

Automated malignancy detection in breast histopathological images

A Chekkoury, P Khurd, J Ni… - Medical Imaging …, 2012 - spiedigitallibrary.org
Detection of malignancy from histopathological images of breast cancer is a labor-intensive
and error-prone process. To streamline this process, we present an efficient Computer Aided …

[HTML][HTML] Spatial heterogeneity of oxygenation and haemodynamics in breast cancer resolved in vivo by conical multispectral optoacoustic mesoscopy

J Li, A Chekkoury, J Prakash, S Glasl… - Light: Science & …, 2020 - nature.com
The characteristics of tumour development and metastasis relate not only to genomic
heterogeneity but also to spatial heterogeneity, associated with variations in the intratumoural …

Automated detection of diagnostically relevant regions in H&E stained digital pathology slides

…, A Patel, J Johnson, J Ni, A Chekkoury… - Medical Imaging …, 2012 - spiedigitallibrary.org
We present a computationally efficient method for analyzing H&E stained digital pathology
slides with the objective of discriminating diagnostically relevant vs. irrelevant regions. Such …

Artificial intelligence with statistical confidence scores for detection of acute or subacute hemorrhage on noncontrast CT head scans

…, E Eibenberger, A Chekkoury… - Radiology: Artificial …, 2022 - pubs.rsna.org
Purpose To present a method that automatically detects, subtypes, and locates acute or
subacute intracranial hemorrhage (ICH) on noncontrast CT (NCCT) head scans; generates …

Ultra-wideband three-dimensional optoacoustic tomography

J Gateau, A Chekkoury, V Ntziachristos - Optics letters, 2013 - opg.optica.org
Broadband optoacoustic waves generated by biological tissues excited with nanosecond
laser pulses carry information corresponding to a wide range of geometrical scales. Typically, …

[HTML][HTML] High-resolution multispectral optoacoustic tomography of the vascularization and constitutive hypoxemia of cancerous tumors

A Chekkoury, A Nunes, J Gateau, P Symvoulidis… - Neoplasia, 2016 - Elsevier
Diversity of the design and alignment of illumination and ultrasonic transducers empower
the fine scalability and versatility of optoacoustic imaging. In this study, we implement an …

Selective plane illumination optical and optoacoustic microscopy for postembryonic imaging

HCA Lin, A Chekkoury, M Omar… - Laser & Photonics …, 2015 - Wiley Online Library
Intravital imaging of large specimens is intrinsically challenging for postembryonic studies.
Selective plane illumination microscopy (SPIM) has been introduced to volumetrically …

High-resolution optoacoustic mesoscopy with a 24 MHz multidetector translate-rotate scanner

J Gateau, A Chekkoury… - Journal of biomedical …, 2013 - spiedigitallibrary.org
Optoacoustic (photoacoustic) mesoscopy aims at high-resolution optical imaging of
anatomical, functional, and cellular parameters at depths that go well beyond those of optical-…

Beyond Early Development: Observing Zebrafish over 6 Weeks with Hybrid Optical and Optoacoustic Imaging

…, C Dietrich, W Hellmich, A Chekkoury… - Laser & Photonics …, 2023 - Wiley Online Library
Zebrafish are common model organisms in developmental biology, but have recently
emerged as imaging targets of research in cancer, tissue regeneration, metabolic disorders, …