CRISPR-Cas-mediated genome editing relies on guide RNAs that direct site-specific DNA
cleavage facilitated by the Cas endonuclease. Here we report that chemical alterations to …

Parts I and II of this paper describe the extension and testing of two sets of Boussinesq-type
equations to include surf zone phenomena. Part I is restricted to 1D tests of shoaling, …

Purpose: The use of 90 Y-microspheres to treat unresectable liver metastases originating
from a variety of neuroendocrine tumors was reviewed. Materials and Methods: This is a …

INTRODUCTION: Radioactive microsphere 90 Y therapy is increasingly used for primary and
metastatic solid tumors in the liver. We present an analysis of 4 explanted livers previously …

In this paper, we focus on the implementation and verification of an extended Boussinesq
model for surf zone hydrodynamics in two horizontal dimensions. The time-domain numerical …

Purpose: Salvage therapy for patients with unresectable colorectal liver metastases that were
refractory to oxaliplatin and irinotecan was performed via radioactive microspheres. High …

The question is posed: “what limits the presence, distribution, and abundance of life in
Antarctica?” Traditionally, continental isolation has been considered to restrict the arrival of new …

Background.Tumor hypoxia may be associated with treatment resistance, cell proliferation,
and metastatic potential, which contribute to poor prognosis. Complementary techniques for …

Management of hepatic malignancies is a ubiquitous medical problem. Surgical resection of
primary or metastatic liver cancer, with or without adjuvant chemotherapy, is the most …

This paper considers the use of meiofauna (benthic metazoa 45 to 500 μm in size) as
biological indicators for monitoring marine environmental health. To date, this abundant and …