In eukaryotes, diploid cells give rise to haploid cells via meiosis, a program of two cell divisions
preceded by one round of DNA replication. Although key molecular components of the …

The transition from mitosis to meiosis is a defining juncture in the life cycle of sexually
reproducing organisms. In yeast, the decision to enter meiosis is made before the single round of …

Microcephaly is a neurodevelopmental disorder causing significantly reduced cerebral cortex
size. Many known microcephaly gene products localize to centrosomes, regulating cell …

Mammalian spermatogenesis—the transformation of stem cells into millions of haploid
spermatozoa—is elaborately organized in time and space. We explored the underlying regulatory …

Synaptotagmin has been proposed to function as a Ca 2+ sensor that regulates synaptic
vesicle exocytosis, whereas the solubleN-ethylmaleimide-sensitive factor attachment protein …

Group 2 Innate lymphoid cells (ILC2) contribute significantly to allergic inflammation. However,
the role of microbiota on ILC2s remains to be unraveled. Here we show that short chain …

Oogenesis is the process by which ovarian germ cells undertake meiosis and differentiate to
become eggs. In mice, Stra8 is required for the chromosomal events of meiosis to occur, but …

The building evidence for the contribution of microbiota to human disease has spurred an
effort to develop therapies that target the gut microbiota. This is particularly evident in …

We identified the gene carrying the juvenile spermatogonial depletion mutation (jsd), a
recessive spermatogenic defect mapped to mouse chromosome 1 (refs. 1 , 2 ). We localized jsd …

A total of 1,991 group B streptococcus (GBS) isolates, collected in 2008 and 2009, were tested
for non-penicillin susceptibility by broth microdilution, disk testing, and oxacillin screening …