User profiles for Andrew C McAvoy
Andrew C. McAvoyPhD Candidate, Georgia Institute of Technology Verified email at gatech.edu Cited by 239 |
[HTML][HTML] Metabolomic profiling of Burkholderia cenocepacia in synthetic cystic fibrosis sputum medium reveals nutrient environment-specific production of virulence …
Infections by Burkholderia cenocepacia lead to life-threatening disease in immunocompromised
individuals, including those living with cystic fibrosis (CF). While genetic variation in …
individuals, including those living with cystic fibrosis (CF). While genetic variation in …
Molecular and microbial microenvironments in chronically diseased lungs associated with cystic fibrosis
To visualize the personalized distributions of pathogens and chemical environments,
including microbial metabolites, pharmaceuticals, and their metabolic products, within and …
including microbial metabolites, pharmaceuticals, and their metabolic products, within and …
[HTML][HTML] A community resource for paired genomic and metabolomic data mining
…, D Männle, C Martin H, AC McAvoy… - Nature Chemical …, 2021 - nature.com
Genomics and metabolomics are widely used to explore specialized metabolite diversity.
The Paired Omics Data Platform is a community initiative to systematically document links …
The Paired Omics Data Platform is a community initiative to systematically document links …
Differences in Cystic Fibrosis-Associated Burkholderia spp. Bacteria Metabolomes after Exposure to the Antibiotic Trimethoprim
AC McAvoy, O Jaiyesimi, PH Threatt… - ACS Infectious …, 2020 - ACS Publications
The Burkholderia cepacia complex is a group of closely related bacterial species with large
genomes that infect immunocompromised individuals and those living with cystic fibrosis. …
genomes that infect immunocompromised individuals and those living with cystic fibrosis. …
Discovery of homogentisic acid as a precursor in trimethoprim metabolism and natural product biosynthesis
AC McAvoy, PH Threatt, J Kapcia III… - ACS Chemical …, 2022 - ACS Publications
Opportunistic infections by Burkholderia cenocepacia are life threatening for patients
suffering from cystic fibrosis and chronic granulomatous disease. These infections are often …
suffering from cystic fibrosis and chronic granulomatous disease. These infections are often …
HIV maintains an evolving and dispersed population in multiple tissues during suppressive combined antiretroviral therapy in individuals with cancer
While combined antiretroviral therapy (cART) can result in undetectable plasma viral loads,
it does not eradicate HIV infection. Furthermore, HIV-infected individuals while on cART …
it does not eradicate HIV infection. Furthermore, HIV-infected individuals while on cART …
A universal language for finding mass spectrometry data patterns
Even though raw mass spectrometry data is information rich, the vast majority of the data is
underutilized. The ability to interrogate these rich datasets is handicapped by the limited …
underutilized. The ability to interrogate these rich datasets is handicapped by the limited …
The Molecular and Microbial Microenvironments in Chronically Diseased Lungs
To visualize the personalized distributions of pathogens, chemical environments including
microbial metabolites, pharmaceuticals, and their metabolic products within and between …
microbial metabolites, pharmaceuticals, and their metabolic products within and between …
[HTML][HTML] Immunogenicity and efficacy of a novel multi-antigenic peptide vaccine based on cross-reactivity between feline and human immunodeficiency viruses
For the development of an effective HIV-1 vaccine, evolutionarily conserved epitopes
between feline and human immunodeficiency viruses (FIV and HIV-1) were determined by …
between feline and human immunodeficiency viruses (FIV and HIV-1) were determined by …
Molecular networking-based strategies in mass spectrometry coupled with in silico dereplication of peptidic natural products and gene cluster analysis
Peptidic natural products (PNPs) are valuable sources for drug development as they are
often associated with desirable bioactivities. Chemoenzymatic approaches coupled with …
often associated with desirable bioactivities. Chemoenzymatic approaches coupled with …