User profiles for Andrew C McAvoy

Andrew C. McAvoy

PhD Candidate, Georgia Institute of Technology
Verified email at gatech.edu
Cited by 239

[HTML][HTML] Metabolomic profiling of Burkholderia cenocepacia in synthetic cystic fibrosis sputum medium reveals nutrient environment-specific production of virulence …

OA Jaiyesimi, AC McAvoy, DN Fogg, N Garg - Scientific reports, 2021 - nature.com
Infections by Burkholderia cenocepacia lead to life-threatening disease in immunocompromised
individuals, including those living with cystic fibrosis (CF). While genetic variation in …

Molecular and microbial microenvironments in chronically diseased lungs associated with cystic fibrosis

…, Y Vázquez-Baeza, AA Aksenov, E Hyde, AC McAvoy… - Msystems, 2019 - Am Soc Microbiol
To visualize the personalized distributions of pathogens and chemical environments,
including microbial metabolites, pharmaceuticals, and their metabolic products, within and …

[HTML][HTML] A community resource for paired genomic and metabolomic data mining

…, D Männle, C Martin H, AC McAvoy… - Nature Chemical …, 2021 - nature.com
Genomics and metabolomics are widely used to explore specialized metabolite diversity.
The Paired Omics Data Platform is a community initiative to systematically document links …

Differences in Cystic Fibrosis-Associated Burkholderia spp. Bacteria Metabolomes after Exposure to the Antibiotic Trimethoprim

AC McAvoy, O Jaiyesimi, PH Threatt… - ACS Infectious …, 2020 - ACS Publications
The Burkholderia cepacia complex is a group of closely related bacterial species with large
genomes that infect immunocompromised individuals and those living with cystic fibrosis. …

Discovery of homogentisic acid as a precursor in trimethoprim metabolism and natural product biosynthesis

AC McAvoy, PH Threatt, J Kapcia III… - ACS Chemical …, 2022 - ACS Publications
Opportunistic infections by Burkholderia cenocepacia are life threatening for patients
suffering from cystic fibrosis and chronic granulomatous disease. These infections are often …

HIV maintains an evolving and dispersed population in multiple tissues during suppressive combined antiretroviral therapy in individuals with cancer

…, OG Pybus, JJ Dollar, SA Maruniak, AC McAvoy… - Journal of …, 2016 - Am Soc Microbiol
While combined antiretroviral therapy (cART) can result in undetectable plasma viral loads,
it does not eradicate HIV infection. Furthermore, HIV-infected individuals while on cART …

A universal language for finding mass spectrometry data patterns

…, GT Luu, TL Knaan, MT Marty, AC McAvoy… - bioRxiv, 2022 - biorxiv.org
Even though raw mass spectrometry data is information rich, the vast majority of the data is
underutilized. The ability to interrogate these rich datasets is handicapped by the limited …

The Molecular and Microbial Microenvironments in Chronically Diseased Lungs

…, Y Vázquez-Baeza, AA Aksenov, E Hyde, AC McAvoy… - bioRxiv, 2019 - biorxiv.org
To visualize the personalized distributions of pathogens, chemical environments including
microbial metabolites, pharmaceuticals, and their metabolic products within and between …

[HTML][HTML] Immunogenicity and efficacy of a novel multi-antigenic peptide vaccine based on cross-reactivity between feline and human immunodeficiency viruses

B Sahay, AM Aranyos, M Mishra, AC McAvoy… - Viruses, 2019 - mdpi.com
For the development of an effective HIV-1 vaccine, evolutionarily conserved epitopes
between feline and human immunodeficiency viruses (FIV and HIV-1) were determined by …

Molecular networking-based strategies in mass spectrometry coupled with in silico dereplication of peptidic natural products and gene cluster analysis

AC McAvoy, N Garg - Methods in Enzymology, 2022 - Elsevier
Peptidic natural products (PNPs) are valuable sources for drug development as they are
often associated with desirable bioactivities. Chemoenzymatic approaches coupled with …