User profiles for Andrew D. Bates

Andrew D Bates

University of Liverpool
Verified email at liv.ac.uk
Cited by 3074

[BOOK][B] DNA topology

AD Bates, A Maxwell - 2005 - books.google.com
DNA as the genetic material is a topic of intense interest in the 21st century, with the genomes
of many organisms having been sequenced. The double helix structure discovered by …

The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix: possible …

…, A Stasiak, J Dubochet, EH Egelman, AD Bates - Journal of molecular …, 1994 - Elsevier
A cryo-electron microscopy study of supercoiled DNA molecules freely suspended in cryo-vitrified
buffer was combined with Monte Carlo simulations and gel electrophoretic analysis to …

A model for the mechanism of strand passage by DNA gyrase

SC Kampranis, AD Bates… - Proceedings of the …, 1999 - National Acad Sciences
The mechanism of type II DNA topoisomerases involves the formation of an enzyme-operated
gate in one double-stranded DNA segment and the passage of another segment through …

[PDF][PDF] Towards multistep nanostructure synthesis: programmed enzymatic self-assembly of DNA/gold systems

AG Kanaras, Z Wang, AD Bates… - Angewandte Chemie …, 2003 - licn.phys.soton.ac.uk
The programmed self-assembly of nanostructures from welldefined units is an important aim
in nanoscience.[1, 2] The use of gold nanoparticles stabilized by thiol-modified DNA is a …

[HTML][HTML] Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides

…, CEM Stevenson, BW Hoogenboom, AD Bates… - Nature …, 2021 - nature.com
In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled)
structures. It remains unclear how this supercoiling affects the detailed double-helical …

The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks

AD Bates, JM Berger, A Maxwell - Nucleic acids research, 2011 - academic.oup.com
Type II DNA topoisomerases (topos) catalyse changes in DNA topology by passing one
double-stranded DNA segment through another. This reaction is essential to processes such as …

Energy coupling in type II topoisomerases: why do they hydrolyze ATP?

AD Bates, A Maxwell - Biochemistry, 2007 - ACS Publications
Type II topoisomerases are essential enzymes in all cells. They help to solve the topological
problems of DNA by passing one double helix through a transient break in another, in a …

Variable‐temperature measurements of the single‐molecule conductance of double‐stranded DNA

H van Zalinge, DJ Schiffrin, AD Bates… - Angewandte …, 2006 - Wiley Online Library
There has been much interest in the electrical properties of DNA.[1] Recent studies have shown
that it is possible to record the current–voltage characteristics of both singlestranded and …

How do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of nonsupercoiling type II …

…, AJ Schoeffler, KD Corbett, JM Berger, AD Bates… - Journal of molecular …, 2009 - Elsevier
DNA topoisomerases control the topology of DNA (eg, the level of supercoiling) in all cells.
Type IIA topoisomerases are ATP-dependent enzymes that have been shown to simplify the …

[PDF][PDF] DNA topology: topoisomerases keep it simple

AD Bates, A Maxwell - Current Biology, 1997 - cell.com
Bates* and Anthony Maxwell† … E-mail: bates@liv.ac.uk. †Department of Biochemistry,
University of Leicester, University Road, Leicester, LE1 7RH, UK. E-mail: ony@le.ac.uk …