Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer

…, BA Foster, C Madias, AL Feldhaus… - Proceedings of the …, 1997 - National Acad Sciences
The identification of potentially useful immune-based treatments for prostate cancer has been
severely constrained by the scarcity of relevant animal research models for this disease. …

[HTML][HTML] Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF α and β receptor

…, TR Bukowski, M Moore, AL Feldhaus… - Journal of Biological …, 2001 - ASBMB
We have characterized platelet-derived growth factor (PDGF) C, a novel growth factor
belonging to the PDGF family. PDGF-C is a multidomain protein with the N-terminal region …

A female-specific role for calcitonin gene-related peptide (CGRP) in rodent pain models

…, GL Mejia, C Driskill, F Ferrini, AL Feldhaus… - Journal of …, 2022 - Soc Neuroscience
We aimed to investigate a sexually dimorphic role of calcitonin gene-related peptide (CGRP)
in rodent models of pain. Based on findings in migraine where CGRP has a preferential …

The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex.

…, E Baker, GR Sutherland, AL Feldhaus… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
CD69 is a rapidly induced T cell activation Ag that is also expressed in an inducible fashion
on cells of most, if not all, hematopoietic lineages. Molecular cloning has shown that CD69 is …

Exogenous PDGF-D is a potent mesangial cell mitogen and causes a severe mesangial proliferative glomerulopathy

…, S Topouzis, AC Haran, AL Feldhaus… - Journal of the …, 2004 - journals.lww.com
ABSTRACT. The PDGF family consists of at least four members, PDGF-A,-B,-C, and-D. All of
the PDGF isoforms bind and signal through two known receptors, PDGF receptor-α and …

Molecular cloning, chromosome mapping and characterization of UBQLN3 a testis-specific gene that contains an ubiquitin-like domain

…, S Holderman, TE Whitmore, M Maurer, AL Feldhaus - Gene, 2000 - Elsevier
The sequence of the ubiquitin protein is highly conserved between species and has facilitated
the cloning of numerous ubiquitin-like proteins. In the present study, we report the cloning …

ALD1613, a novel long-acting monoclonal antibody to control ACTH-driven pharmacology

AL Feldhaus, K Anderson, B Dutzar, E Ojala… - …, 2017 - academic.oup.com
Adrenocorticotropic hormone (ACTH) is the primary regulator of adrenal glucocorticoid
production. Elevated levels of ACTH play a critical role in disease progression in several …

BLyF, a Novel Cell-Type- and Stage-Specific Regulator of the B-Lymphocyte Gene mb-1

AL Feldhaus, D Mbangkollo, KL Arvin… - … and cellular biology, 1992 - Taylor & Francis
The mb-1 gene encodes an integral membrane protein that appears to be required for the
surface expression and signalling function(s) of the immunoglobulin receptor on B …

HTF4: a new human helix-loop-helix protein.

Y Zhang, J Babin, AL Feldhaus, H Singh… - Nucleic acids …, 1991 - ncbi.nlm.nih.gov
By screening an expression library (9) prepared from HeLa cells, we have isolated a cDNA
encoding HTF4, a new member of the human helix-loop-helix family of proteins. HTF4 binds …

Targeted disruption of the Oct‐2 locus in a B cell provides genetic evidence for two distinct cell type‐specific pathways of octamer element‐mediated gene activation.

AL Feldhaus, CA Klug, KL Arvin, H Singh - The EMBO Journal, 1993 - embopress.org
The Oct‐2 protein is a tissue‐specific POU‐homeodomain transcription factor. It has been
considered to represent a developmental regulator of immunoglobulin gene expression by …